ID   YF36_SCHPO              Reviewed;         429 AA.
AC   O13897;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Uncharacterized hydrolase C22A12.06c;
DE            EC=3.1.-.-;
GN   ORFNames=SPAC22A12.06c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}. Note=Localizes at the barrier septum and
CC       cell tip.
CC   -!- SIMILARITY: Belongs to the AB hydrolase 3 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAB16576.1; -; Genomic_DNA.
DR   PIR; T38146; T38146.
DR   RefSeq; NP_593236.1; NM_001018633.2.
DR   AlphaFoldDB; O13897; -.
DR   SMR; O13897; -.
DR   BioGRID; 277926; 1.
DR   STRING; 4896.SPAC22A12.06c.1; -.
DR   ESTHER; schpo-C22A12.06C; FSH1.
DR   iPTMnet; O13897; -.
DR   MaxQB; O13897; -.
DR   PaxDb; O13897; -.
DR   PRIDE; O13897; -.
DR   EnsemblFungi; SPAC22A12.06c.1; SPAC22A12.06c.1:pep; SPAC22A12.06c.
DR   GeneID; 2541420; -.
DR   KEGG; spo:SPAC22A12.06c; -.
DR   PomBase; SPAC22A12.06c; -.
DR   VEuPathDB; FungiDB:SPAC22A12.06c; -.
DR   eggNOG; KOG2551; Eukaryota.
DR   HOGENOM; CLU_627245_0_0_1; -.
DR   InParanoid; O13897; -.
DR   OMA; CRCTKRI; -.
DR   PhylomeDB; O13897; -.
DR   PRO; PR:O13897; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0032153; C:cell division site; HDA:PomBase.
DR   GO; GO:0051286; C:cell tip; HDA:PomBase.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0016787; F:hydrolase activity; IBA:GO_Central.
DR   GO; GO:0017171; F:serine hydrolase activity; ISM:PomBase.
DR   Gene3D; 3.40.430.10; -; 1.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR024072; DHFR-like_dom_sf.
DR   InterPro; IPR005645; FSH_dom.
DR   Pfam; PF03959; FSH1; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase; Nucleus; Reference proteome.
FT   CHAIN           1..429
FT                   /note="Uncharacterized hydrolase C22A12.06c"
FT                   /id="PRO_0000316196"
FT   ACT_SITE        116
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        179
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        206
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   429 AA;  48231 MW;  8A1D0EB7D88D05EC CRC64;
     MKSATKSKIL CIHGYAESGE LFSVKLRALR ERMADSVDFY FPTGPIELDK AKDELNGSGF
     DALSTVFSSS PASHRRGWWR INEYADTKQL EPTKAFEYLA SYIKEHGPFD GILGFSQGTN
     LAANLAALVT IPKYQEYFSQ PPFRFALFFS GYFRPLLMDG AVHATKLDLP TLHLLGKYDT
     VLSTETSTTL VRACKDAQVL FHPAAHQIPA PHAYVEPAAD FIDFFSREDW PIISKHISLI
     VPTKKVNTTS AQTSLNNVEH DLISKIMSRS FKGGINVVVS DLQMFNEYKR IFGPKVLSLV
     VTDGQEPDTY SENVHYTPNF KGALAYLEAY QNSIGRIYVI GDKKLLTLGM LCRCTKRIIA
     ITDAEDKFIS QSSAQQVSGS LPFLEHSKEW LKAKSSQIRQ WTGQSRLKHM SQDNSGEPVT
     MKLQMWERL