ID   YFAS1_KLULA             Reviewed;         266 AA.
AC   Q6CMY2;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=FAS1 domain-containing protein KLLA0E16841g;
DE   Flags: Precursor;
GN   OrderedLocusNames=KLLA0E16841g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- SUBCELLULAR LOCATION: Vacuole {ECO:0000250}.
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DR   EMBL; CR382125; CAG99794.1; -; Genomic_DNA.
DR   RefSeq; XP_454707.1; XM_454707.1.
DR   AlphaFoldDB; Q6CMY2; -.
DR   EnsemblFungi; CAG99794; CAG99794; KLLA0_E16787g.
DR   GeneID; 2893941; -.
DR   KEGG; kla:KLLA0_E16787g; -.
DR   eggNOG; ENOG502S5NC; Eukaryota.
DR   HOGENOM; CLU_076942_0_0_1; -.
DR   InParanoid; Q6CMY2; -.
DR   Proteomes; UP000000598; Chromosome E.
DR   GO; GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.30.180.10; -; 1.
DR   InterPro; IPR036378; FAS1_dom_sf.
DR   InterPro; IPR000782; FAS1_domain.
DR   InterPro; IPR040200; Mug57-like.
DR   PANTHER; PTHR28156; PTHR28156; 1.
DR   Pfam; PF02469; Fasciclin; 1.
DR   SUPFAM; SSF82153; SSF82153; 1.
DR   PROSITE; PS50213; FAS1; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal; Vacuole.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..266
FT                   /note="FAS1 domain-containing protein KLLA0E16841g"
FT                   /id="PRO_0000008797"
FT   DOMAIN          105..263
FT                   /note="FAS1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00082"
SQ   SEQUENCE   266 AA;  30016 MW;  C696E491AC25AA62 CRC64;
     MRLNILSTLL LLGAIDKVVA RRVLNLDSLD VSDSDSKNEK REPKRLPLDI EGIMAGHDEA
     MDKRDARRIG LNVDGLSDSE LRLRKRDLRR PQFVLDITQG KVEERVNLDS RLAILQDISL
     FSEYGRDVTE VVAQWEDRSQ ELIVIAPTND AISKLSMKPW QFPNNIDAME QSNAEPKQID
     DAIKENVAHF VKSHIVAHSD DFDLESDEIW LHSEADTSEK GDIVLKRQNN EYFVASASNM
     DFKLVKTVDV AANGVILIID SSLITP