YFAS1_YEAST
ID YFAS1_YEAST Reviewed; 272 AA.
AC Q12331; D6VSP6;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=FAS1 domain-containing protein YDR262W;
DE Flags: Precursor;
GN OrderedLocusNames=YDR262W; ORFNames=YD9320B.01;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169867;
RA Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G.,
RA Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C.,
RA Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F.,
RA Delaveau T., del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M.,
RA Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T.,
RA Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C.,
RA Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S.,
RA Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L.,
RA Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H.,
RA Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M.,
RA Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M.,
RA Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A.,
RA Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G.,
RA Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E.,
RA Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S.,
RA Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D.,
RA Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V.,
RA Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E.,
RA Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M.,
RA Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D.,
RA Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X.,
RA Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A.,
RA Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R.,
RA Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T.,
RA Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L.,
RA Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E.,
RA Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L.,
RA Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M.,
RA Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K.,
RA Mewes H.-W., Zollner A., Zaccaria P.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.";
RL Nature 387:75-78(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP PROTEIN SEQUENCE OF 72-89 AND 234-244, AND IDENTIFICATION BY MASS
RP SPECTROMETRY.
RA Bienvenut W.V., Peters C.;
RL Submitted (MAY-2005) to UniProtKB.
RN [5]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [6]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- SUBCELLULAR LOCATION: Vacuole {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 4846 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; Z68290; CAA92580.1; -; Genomic_DNA.
DR EMBL; Z70202; CAA94101.1; -; Genomic_DNA.
DR EMBL; Z74387; CAA98911.1; -; Genomic_DNA.
DR EMBL; AY557738; AAS56064.1; -; Genomic_DNA.
DR EMBL; BK006938; DAA12106.1; -; Genomic_DNA.
DR PIR; S61117; S61117.
DR RefSeq; NP_010548.3; NM_001180570.3.
DR AlphaFoldDB; Q12331; -.
DR BioGRID; 32318; 50.
DR DIP; DIP-8945N; -.
DR IntAct; Q12331; 1.
DR STRING; 4932.YDR262W; -.
DR MaxQB; Q12331; -.
DR PaxDb; Q12331; -.
DR PRIDE; Q12331; -.
DR EnsemblFungi; YDR262W_mRNA; YDR262W; YDR262W.
DR GeneID; 851855; -.
DR KEGG; sce:YDR262W; -.
DR SGD; S000002670; YDR262W.
DR VEuPathDB; FungiDB:YDR262W; -.
DR eggNOG; ENOG502S17N; Eukaryota.
DR HOGENOM; CLU_076942_0_0_1; -.
DR InParanoid; Q12331; -.
DR OMA; IDSCLEW; -.
DR BioCyc; YEAST:G3O-29832-MON; -.
DR PRO; PR:Q12331; -.
DR Proteomes; UP000002311; Chromosome IV.
DR RNAct; Q12331; protein.
DR GO; GO:0000324; C:fungal-type vacuole; HDA:SGD.
DR InterPro; IPR000782; FAS1_domain.
DR InterPro; IPR040200; Mug57-like.
DR PANTHER; PTHR28156; PTHR28156; 1.
DR PROSITE; PS50213; FAS1; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Reference proteome; Signal; Vacuole.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..272
FT /note="FAS1 domain-containing protein YDR262W"
FT /id="PRO_0000008801"
FT DOMAIN 100..269
FT /note="FAS1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00082"
SQ SEQUENCE 272 AA; 30634 MW; D099BD0A2568A63C CRC64;
MIFNLPVSVL LYFSLIWAME PSFVRGKNVV NLITFKDSNG KLHKRLAPEE IPPRLHNSQV
NSYPLGYKGM RDFSRPAVNL DDILGTQQRK QQEFLAELSP LSLESKLSLV NEVQIFASYV
RNDVETYNKV SDPNEDLIII APTNRAVSQL TLKPWQFPNN IDKLESDGAT EKELDTAIQE
NISKFVRSHI VVYNDDKNSY KKVSPGCTLL QSIDFTESKK SDSETGGDIL LKKEGEVYYV
ASSRDEKFHA VESIENGSNG VILMVDFTLV GP
