YFBS_ECO57
ID YFBS_ECO57 Reviewed; 610 AA.
AC P0AFU3; P76935; P77741;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Uncharacterized transporter YfbS;
GN Name=yfbS; OrderedLocusNames=Z3553, ECs3176;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CitM (TC 2.A.11) transporter family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE005174; AAG57421.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB36599.1; -; Genomic_DNA.
DR PIR; H91025; H91025.
DR RefSeq; NP_311203.1; NC_002695.1.
DR RefSeq; WP_001012899.1; NZ_SDVX01000004.1.
DR AlphaFoldDB; P0AFU3; -.
DR STRING; 155864.EDL933_3456; -.
DR EnsemblBacteria; AAG57421; AAG57421; Z3553.
DR EnsemblBacteria; BAB36599; BAB36599; ECs_3176.
DR GeneID; 66673825; -.
DR GeneID; 916884; -.
DR KEGG; ece:Z3553; -.
DR KEGG; ecs:ECs_3176; -.
DR PATRIC; fig|386585.9.peg.3314; -.
DR eggNOG; COG0471; Bacteria.
DR eggNOG; COG0490; Bacteria.
DR HOGENOM; CLU_005170_6_1_6; -.
DR OMA; IHWQSLV; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; -; 2.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR InterPro; IPR031312; Na/sul_symport_CS.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR Pfam; PF03600; CitMHS; 2.
DR Pfam; PF02080; TrkA_C; 2.
DR SUPFAM; SSF116726; SSF116726; 2.
DR PROSITE; PS01271; NA_SULFATE; 1.
DR PROSITE; PS51202; RCK_C; 2.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..610
FT /note="Uncharacterized transporter YfbS"
FT /id="PRO_0000172504"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 373..393
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 425..445
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 464..484
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 503..523
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 543..563
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 588..608
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 218..307
FT /note="RCK C-terminal 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
FT DOMAIN 314..398
FT /note="RCK C-terminal 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
SQ SEQUENCE 610 AA; 65872 MW; 57100587B0F54C9F CRC64;
MNGELIWVLS LLAVAIVLFA TGRVRMDAVA LFVIVAFALS GTLTVPEVFS GFSDPNVVLI
AALFIIGDGL VRTGVATVMG TWLVKVAGNS EIKMLVLLML TVAGLGAFMS STGVVAIFIP
VVLSVAMRMQ TSPSRLMMPL SFAGLISGMM TLVATPPNLV VNSELLREGY HGFSFFSVTP
IGLVVLVLGI LYMLVMRFML KGDTQTPQRE GWTRRTFRDL IREYRLTGRA RRLAIRPGSP
MIGQRLDDLK LRERYGANVI GVERWRRFRR VIVNVNGVSE FRARDVLLID MSAADVDLRQ
FCSEQLLEPM VLRGEYFSDQ ALDVGMAEIS LIPESELIGK SVREIGFRTR YGLNVVGLKR
NGVALEGSLA DEPLLLGDII LVVGNWKLIG MLAKQGRDFV ALNLPEEVSE ASPAHSQAPH
AIFCLVLMVA LMLTDEIPNP VAAIIACLLM GKFRCIDAES AYKSIHWPSI ILIVGMMPFA
VALQKTGGVA LAVKGLMDIG GGYGPHMMLG CLFVLSAVIG LFISNTATAV LMAPIALAAA
KTMGVSPYPF AMVVAMAASA AFMTPVSSPV NTLVLGPGNY SFSDFVKLGV PFTIIVMAVC
VVMIPMLFPF
