YFBS_ECOLI
ID YFBS_ECOLI Reviewed; 610 AA.
AC P0AFU2; P76935; P77741;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Uncharacterized transporter YfbS;
GN Name=yfbS; OrderedLocusNames=b2292, JW2289;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT its sequence features.";
RL DNA Res. 4:91-113(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CitM (TC 2.A.11) transporter family.
CC {ECO:0000305}.
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DR EMBL; U00096; AAC75352.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA16128.1; -; Genomic_DNA.
DR PIR; B65001; B65001.
DR RefSeq; NP_416795.1; NC_000913.3.
DR RefSeq; WP_001012899.1; NZ_STEB01000008.1.
DR AlphaFoldDB; P0AFU2; -.
DR BioGRID; 4262968; 215.
DR DIP; DIP-48033N; -.
DR IntAct; P0AFU2; 1.
DR STRING; 511145.b2292; -.
DR TCDB; 2.A.47.4.8; the divalent anion:na(+) symporter (dass) family.
DR jPOST; P0AFU2; -.
DR PaxDb; P0AFU2; -.
DR PRIDE; P0AFU2; -.
DR EnsemblBacteria; AAC75352; AAC75352; b2292.
DR EnsemblBacteria; BAA16128; BAA16128; BAA16128.
DR GeneID; 66673825; -.
DR GeneID; 946766; -.
DR KEGG; ecj:JW2289; -.
DR KEGG; eco:b2292; -.
DR PATRIC; fig|1411691.4.peg.4443; -.
DR EchoBASE; EB3856; -.
DR eggNOG; COG0471; Bacteria.
DR eggNOG; COG0490; Bacteria.
DR HOGENOM; CLU_005170_6_1_6; -.
DR InParanoid; P0AFU2; -.
DR OMA; IHWQSLV; -.
DR PhylomeDB; P0AFU2; -.
DR BioCyc; EcoCyc:G7186-MON; -.
DR PRO; PR:P0AFU2; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; -; 2.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR InterPro; IPR031312; Na/sul_symport_CS.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR Pfam; PF03600; CitMHS; 2.
DR Pfam; PF02080; TrkA_C; 2.
DR SUPFAM; SSF116726; SSF116726; 2.
DR PROSITE; PS01271; NA_SULFATE; 1.
DR PROSITE; PS51202; RCK_C; 2.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..610
FT /note="Uncharacterized transporter YfbS"
FT /id="PRO_0000172503"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 373..393
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 425..445
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 464..484
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 503..523
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 543..563
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 588..608
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 218..307
FT /note="RCK C-terminal 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
FT DOMAIN 314..398
FT /note="RCK C-terminal 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
SQ SEQUENCE 610 AA; 65872 MW; 57100587B0F54C9F CRC64;
MNGELIWVLS LLAVAIVLFA TGRVRMDAVA LFVIVAFALS GTLTVPEVFS GFSDPNVVLI
AALFIIGDGL VRTGVATVMG TWLVKVAGNS EIKMLVLLML TVAGLGAFMS STGVVAIFIP
VVLSVAMRMQ TSPSRLMMPL SFAGLISGMM TLVATPPNLV VNSELLREGY HGFSFFSVTP
IGLVVLVLGI LYMLVMRFML KGDTQTPQRE GWTRRTFRDL IREYRLTGRA RRLAIRPGSP
MIGQRLDDLK LRERYGANVI GVERWRRFRR VIVNVNGVSE FRARDVLLID MSAADVDLRQ
FCSEQLLEPM VLRGEYFSDQ ALDVGMAEIS LIPESELIGK SVREIGFRTR YGLNVVGLKR
NGVALEGSLA DEPLLLGDII LVVGNWKLIG MLAKQGRDFV ALNLPEEVSE ASPAHSQAPH
AIFCLVLMVA LMLTDEIPNP VAAIIACLLM GKFRCIDAES AYKSIHWPSI ILIVGMMPFA
VALQKTGGVA LAVKGLMDIG GGYGPHMMLG CLFVLSAVIG LFISNTATAV LMAPIALAAA
KTMGVSPYPF AMVVAMAASA AFMTPVSSPV NTLVLGPGNY SFSDFVKLGV PFTIIVMAVC
VVMIPMLFPF
