ID   YFCA_ECO57              Reviewed;         269 AA.
AC   P0AD32; P14008;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Probable membrane transporter protein YfcA;
GN   Name=yfcA; OrderedLocusNames=Z3590, ECs3211;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the 4-toluene sulfonate uptake permease (TSUP)
CC       (TC 2.A.102) family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE005174; AAG57456.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB36634.1; -; Genomic_DNA.
DR   PIR; C91030; C91030.
DR   PIR; D85874; D85874.
DR   RefSeq; NP_311238.1; NC_002695.1.
DR   RefSeq; WP_000447361.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0AD32; -.
DR   STRING; 155864.EDL933_3495; -.
DR   EnsemblBacteria; AAG57456; AAG57456; Z3590.
DR   EnsemblBacteria; BAB36634; BAB36634; ECs_3211.
DR   GeneID; 67416757; -.
DR   GeneID; 915693; -.
DR   KEGG; ece:Z3590; -.
DR   KEGG; ecs:ECs_3211; -.
DR   PATRIC; fig|386585.9.peg.3352; -.
DR   eggNOG; COG0730; Bacteria.
DR   HOGENOM; CLU_045498_2_1_6; -.
DR   OMA; YAYGFIM; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002781; TM_pro_TauE-like.
DR   Pfam; PF01925; TauE; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..269
FT                   /note="Probable membrane transporter protein YfcA"
FT                   /id="PRO_0000169188"
FT   TOPO_DOM        1..7
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        29..30
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        52..84
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        106..111
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        112..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        133..156
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        178..197
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        219..269
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   269 AA;  28643 MW;  B640B0EBFF1BF7ED CRC64;
     METFNSLFMV SPLLLGVLFF VAMLAGFIDS IAGGGGLLTI PALMAAGMSP ANALATNKLQ
     ACGGSISATI YFIRRKVVSL SDQKLNIAMT FVGSMSGALL VQYVQADVLR QILPILVICI
     GLYFLLMPKL GEEDRQRRMY GLPFALIAGG CVGFYDGFFG PAAGSFYALA FVTLCGFNLA
     KATAHAKLLN ATSNIGGLLL FILGGKVIWA TGFVMLVGQF LGARMGSRLV LSKGQKLIRP
     MIVIVSAVMS AKLLYDSHGQ EILHWLGMN