ID   YFCD_ECO57              Reviewed;         180 AA.
AC   P65558; P76494;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Uncharacterized Nudix hydrolase YfcD;
DE            EC=3.6.-.-;
GN   Name=yfcD; OrderedLocusNames=Z3561, ECs3183;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the Nudix hydrolase family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG57428.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB36606.1; -; Genomic_DNA.
DR   PIR; G91026; G91026.
DR   PIR; H85870; H85870.
DR   RefSeq; NP_311210.1; NC_002695.1.
DR   RefSeq; WP_000437935.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P65558; -.
DR   SMR; P65558; -.
DR   STRING; 155864.EDL933_3464; -.
DR   EnsemblBacteria; AAG57428; AAG57428; Z3561.
DR   EnsemblBacteria; BAB36606; BAB36606; ECs_3183.
DR   GeneID; 67416729; -.
DR   GeneID; 916891; -.
DR   KEGG; ece:Z3561; -.
DR   KEGG; ecs:ECs_3183; -.
DR   PATRIC; fig|386585.9.peg.3323; -.
DR   eggNOG; COG1443; Bacteria.
DR   HOGENOM; CLU_060552_3_0_6; -.
DR   OMA; PGYWDVA; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   InterPro; IPR024195; NUDIX_hydrolase_YfcD_pred.
DR   Pfam; PF00293; NUDIX; 1.
DR   PIRSF; PIRSF017340; Nudix_hydro; 1.
DR   SUPFAM; SSF55811; SSF55811; 1.
DR   PROSITE; PS51462; NUDIX; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Metal-binding; Reference proteome.
FT   CHAIN           1..180
FT                   /note="Uncharacterized Nudix hydrolase YfcD"
FT                   /id="PRO_0000057079"
FT   DOMAIN          35..163
FT                   /note="Nudix hydrolase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00794"
FT   MOTIF           72..94
FT                   /note="Nudix box"
FT   BINDING         88
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         92
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   180 AA;  20376 MW;  83FC88B71EF9D58B CRC64;
     MEQRRLASTE WVDIVNEENE VIAQASREQM RAQCLRHRAT YIVVHDGMGK ILVQRRTETK
     DFLPGMLDAT AGGVVQADEQ LLESARREAE EELGIAGVPF AEHGQFYFED KNCRVWGALF
     SCVSHGPFAL QEDEVSEVCW LTPEEITARC DEFTPDSLKA LALWMKRNAK NEAVETETAE