YFCD_SHIFL
ID YFCD_SHIFL Reviewed; 180 AA.
AC P59196;
DT 10-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT 10-JAN-2003, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Uncharacterized Nudix hydrolase YfcD;
DE EC=3.6.-.-;
GN Name=yfcD; OrderedLocusNames=SF2375, S2510;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC -!- SIMILARITY: Belongs to the Nudix hydrolase family. {ECO:0000305}.
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DR EMBL; AE005674; AAN43888.1; -; Genomic_DNA.
DR EMBL; AE014073; AAP17706.1; -; Genomic_DNA.
DR RefSeq; NP_708181.1; NC_004337.2.
DR RefSeq; WP_000437938.1; NZ_WPGW01000016.1.
DR AlphaFoldDB; P59196; -.
DR SMR; P59196; -.
DR STRING; 198214.SF2375; -.
DR EnsemblBacteria; AAN43888; AAN43888; SF2375.
DR EnsemblBacteria; AAP17706; AAP17706; S2510.
DR GeneID; 1026560; -.
DR GeneID; 58388081; -.
DR KEGG; sfl:SF2375; -.
DR KEGG; sfx:S2510; -.
DR PATRIC; fig|198214.7.peg.2842; -.
DR HOGENOM; CLU_060552_3_0_6; -.
DR OMA; PGYWDVA; -.
DR OrthoDB; 1345242at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR InterPro; IPR024195; NUDIX_hydrolase_YfcD_pred.
DR Pfam; PF00293; NUDIX; 1.
DR PIRSF; PIRSF017340; Nudix_hydro; 1.
DR SUPFAM; SSF55811; SSF55811; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW Hydrolase; Magnesium; Metal-binding; Reference proteome.
FT CHAIN 1..180
FT /note="Uncharacterized Nudix hydrolase YfcD"
FT /id="PRO_0000057082"
FT DOMAIN 35..163
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00794"
FT MOTIF 72..94
FT /note="Nudix box"
FT BINDING 88
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000250"
FT BINDING 92
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000250"
SQ SEQUENCE 180 AA; 20304 MW; 83FC88B5BC73FF8B CRC64;
MEQRRLASTE WVDIVNEENE VIAQASREQM RAQCLRHRAT YIVVHDGMGK ILVQRRTETK
DFLPGMLDAT AGGVVQADEQ LLESARREAE EELGIAGVPF AEHGQFYFED KNCRVWGALF
SCVSHGPFAL QEDEVSGVCW LTPEEITARC DEFTPDSLKA LALWMKRNAK NEAVETETAE
