ID   YFCH_ECOLI              Reviewed;         297 AA.
AC   P77775;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 143.
DE   RecName: Full=Epimerase family protein YfcH;
GN   Name=yfcH; OrderedLocusNames=b2304, JW2301;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA   Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA   Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA   Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA   Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT   "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT   genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT   its sequence features.";
RL   DNA Res. 4:91-113(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. SDR39U1 subfamily. {ECO:0000305}.
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DR   EMBL; U00096; AAC75364.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA16141.1; -; Genomic_DNA.
DR   PIR; F65002; F65002.
DR   RefSeq; NP_416807.1; NC_000913.3.
DR   RefSeq; WP_001028341.1; NZ_LN832404.1.
DR   AlphaFoldDB; P77775; -.
DR   SMR; P77775; -.
DR   BioGRID; 4260519; 81.
DR   DIP; DIP-11981N; -.
DR   IntAct; P77775; 8.
DR   STRING; 511145.b2304; -.
DR   jPOST; P77775; -.
DR   PaxDb; P77775; -.
DR   PRIDE; P77775; -.
DR   EnsemblBacteria; AAC75364; AAC75364; b2304.
DR   EnsemblBacteria; BAA16141; BAA16141; BAA16141.
DR   GeneID; 946784; -.
DR   KEGG; ecj:JW2301; -.
DR   KEGG; eco:b2304; -.
DR   PATRIC; fig|511145.12.peg.2399; -.
DR   EchoBASE; EB3864; -.
DR   eggNOG; COG1090; Bacteria.
DR   HOGENOM; CLU_047373_0_3_6; -.
DR   InParanoid; P77775; -.
DR   OMA; YMPWIHI; -.
DR   PhylomeDB; P77775; -.
DR   BioCyc; EcoCyc:G7196-MON; -.
DR   PRO; PR:P77775; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   InterPro; IPR013549; DUF1731.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR010099; SDR39U1.
DR   Pfam; PF08338; DUF1731; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR01777; yfcH; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..297
FT                   /note="Epimerase family protein YfcH"
FT                   /id="PRO_0000162404"
SQ   SEQUENCE   297 AA;  32699 MW;  C7418CCFC54B674B CRC64;
     MNIVITGGTG LIGRHLIPRL LELGHQITVV TRNPQKASSV LGPRVTLWQG LADQSNLNGV
     DAVINLAGEP IADKRWTHEQ KERLCQSRWN ITQKLVDLIN ASDTPPSVLI SGSATGYYGD
     LGEVVVTEEE PPHNEFTHKL CARWEEIACR AQSDKTRVCL LRTGVVLAPD GGILGKMLPP
     FRLGLGGPIG SGRQYLAWIH IDDMVNGILW LLDNELRGPF NMVSPYPVRN EQFAHALGHA
     LHRPAILRVP ATAIRLLMGE SSVLVLGGQR ALPKRLEEAG FAFRWYDLEE ALADVVR