ID   YFCJ_SALTI              Reviewed;         392 AA.
AC   Q8Z4Z9;
DT   10-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Uncharacterized MFS-type transporter YfcJ {ECO:0000255|HAMAP-Rule:MF_02091};
GN   Name=yfcJ {ECO:0000255|HAMAP-Rule:MF_02091};
GN   OrderedLocusNames=STY2603, t0492;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_02091}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_02091}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. YfcJ family.
CC       {ECO:0000255|HAMAP-Rule:MF_02091}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL513382; CAD07604.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO68198.1; -; Genomic_DNA.
DR   RefSeq; NP_456914.1; NC_003198.1.
DR   RefSeq; WP_000127714.1; NZ_WSUR01000029.1.
DR   AlphaFoldDB; Q8Z4Z9; -.
DR   SMR; Q8Z4Z9; -.
DR   STRING; 220341.16503596; -.
DR   EnsemblBacteria; AAO68198; AAO68198; t0492.
DR   KEGG; stt:t0492; -.
DR   KEGG; sty:STY2603; -.
DR   PATRIC; fig|220341.7.peg.2636; -.
DR   eggNOG; COG2814; Bacteria.
DR   HOGENOM; CLU_001265_10_3_6; -.
DR   OMA; LFVHQEL; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   HAMAP; MF_02091; MFS_YfcJ; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR037541; MFS_YfcJ.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..392
FT                   /note="Uncharacterized MFS-type transporter YfcJ"
FT                   /id="PRO_0000087803"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        151..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        252..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        276..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        342..362
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        369..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
SQ   SEQUENCE   392 AA;  40746 MW;  B966503F83E974D9 CRC64;
     MTAVSQKTTT PSADFSLFRI AFAVFLTYMT VGLPLPVIPL FVHHELGYSN TMVGIAVGIQ
     FFATVLTRGY AGRLADQYGA KRSALQGMLA CGLAGAAWLL AALLPVSAPV KFALLIVGRL
     ILGFGESQLL TGTLTWGLGL VGPTRSGKVM SWNGMAIYGA LAAGAPLGLL IHSHFGFAAL
     AGTTMVLPLL AWAFNGTVRK VPAYTGERPS LWSVVGLIWK PGLGLALQGV GFAVIGTFIS
     LYFVSNGWTM AGFTLTAFGG AFVLMRILFG WMPDRFGGVK VAVVSLLVET AGLLLLWLAP
     TAWIALVGAA LTGAGCSLIF SALGVEVVKR VPAQVRGTAL GGYAAFQDIS YGVTGPLAGM
     LATSYGYPSV FLAGAISAVV GILVTILSFR RG