ID   CBBR_RHIME              Reviewed;         313 AA.
AC   P58332; Q9EXV3;
DT   02-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT   02-NOV-2001, sequence version 1.
DT   25-MAY-2022, entry version 116.
DE   RecName: Full=HTH-type transcriptional regulator CbbR;
DE   AltName: Full=RuBisCO operon transcriptional regulator;
GN   Name=cbbR; OrderedLocusNames=RB0196; ORFNames=SMb20203;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OG   Plasmid pSymB (megaplasmid 2).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1021;
RA   Finan T.M., Aneja P., Chain P., Napper K., Golding B.;
RT   "Mineral phosphate solubilization in Sinorhizobium meliloti.";
RL   Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481431; DOI=10.1073/pnas.161294698;
RA   Finan T.M., Weidner S., Wong K., Buhrmester J., Chain P., Vorhoelter F.J.,
RA   Hernandez-Lucas I., Becker A., Cowie A., Gouzy J., Golding B., Puehler A.;
RT   "The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing
RT   endosymbiont Sinorhizobium meliloti.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9889-9894(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- FUNCTION: Transcriptional activator for the cbb operon for RuBisCO and
CC       other Calvin cycle genes. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY013584; AAG42537.1; -; Genomic_DNA.
DR   EMBL; AL591985; CAC48596.1; -; Genomic_DNA.
DR   PIR; D95866; D95866.
DR   RefSeq; NP_436736.1; NC_003078.1.
DR   RefSeq; WP_003528716.1; NC_003078.1.
DR   AlphaFoldDB; P58332; -.
DR   SMR; P58332; -.
DR   STRING; 266834.SM_b20203; -.
DR   EnsemblBacteria; CAC48596; CAC48596; SM_b20203.
DR   GeneID; 61600211; -.
DR   KEGG; sme:SM_b20203; -.
DR   PATRIC; fig|266834.11.peg.5112; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_1_5; -.
DR   OMA; ACEEYFK; -.
DR   Proteomes; UP000001976; Plasmid pSymB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Plasmid; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..313
FT                   /note="HTH-type transcriptional regulator CbbR"
FT                   /id="PRO_0000105604"
FT   DOMAIN          1..61
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        21..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   313 AA;  34364 MW;  1BB07B3B46B829C7 CRC64;
     MRNVTFRQLR TVEAVCRLGK INLAAEALGL TGPALTLQIQ HLERDAGIAL FDRTRGGMVP
     TAYGLAFLEA ARAIEDSLIA LEDSIDAIKG LRTGRLRLGV VSTGKYFAPQ LIAAFRDQVP
     AVEINLFIGN RAEIIAKLRD HEIDIALMGR PPRDFEVRAQ VFGDHPLVFI APAGHPLAGV
     LEISRERIAQ EQFLVREKGS GTRISLEIFL SDTPHELEEL GTEIASNETI KQAVIAGLGI
     AFISAHTIEQ EVKLGRLVIL DVIDTPIRRQ WFTVSRLDRV ATPAMQAFER FVLASGARYL
     PVVSKPYPAN AFG