ID   CBBR_SINMW              Reviewed;         313 AA.
AC   P56885; A6UGE9;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 2.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=HTH-type transcriptional regulator CbbR;
DE   AltName: Full=RuBisCO operon transcriptional regulator;
GN   Name=cbbR; OrderedLocusNames=Smed_3919;
OS   Sinorhizobium medicae (strain WSM419) (Ensifer medicae).
OG   Plasmid pSMED01.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=366394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Fenner B.J., Tiwari R.P., Dilworth M.J.;
RT   "Genetic regulation of C1 metabolism in Sinorhizobium meliloti.";
RL   Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSM419;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G.,
RA   Richardson P.;
RT   "Complete sequence of Sinorhizobium medicae WSM419 plasmid pSMED01.";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcriptional activator for the cbb operon for RuBisCO and
CC       other Calvin cycle genes.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; AF211846; AAF25374.1; -; Genomic_DNA.
DR   EMBL; CP000739; ABR62729.1; -; Genomic_DNA.
DR   RefSeq; WP_011969551.1; NC_009620.1.
DR   RefSeq; YP_001312662.1; NC_009620.1.
DR   AlphaFoldDB; P56885; -.
DR   SMR; P56885; -.
DR   EnsemblBacteria; ABR62729; ABR62729; Smed_3919.
DR   GeneID; 61612436; -.
DR   KEGG; smd:Smed_3919; -.
DR   PATRIC; fig|366394.8.peg.365; -.
DR   HOGENOM; CLU_039613_6_1_5; -.
DR   OMA; VCKYYLM; -.
DR   OrthoDB; 750230at2; -.
DR   Proteomes; UP000001108; Plasmid pSMED01.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Plasmid; Transcription; Transcription regulation.
FT   CHAIN           1..313
FT                   /note="HTH-type transcriptional regulator CbbR"
FT                   /id="PRO_0000105605"
FT   DOMAIN          1..61
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        21..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   CONFLICT        14
FT                   /note="A -> T (in Ref. 1; AAF25374)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        83
FT                   /note="D -> I (in Ref. 1; AAF25374)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   313 AA;  34164 MW;  26EFDA0FD1ECAA88 CRC64;
     MRNVSLRQLR TVEAVCRLGK INLAAEALGL TGPALTLQIQ HLERDTGVAL FDRTRGGMVP
     TAYGLAFLEA ARAVEDSLAA LEDSIGAISG LRTGRLRLGV VSTGKYFAPQ LIAAFRDQVP
     AVEINLFIGN RAEIIAKLRD HEIDIALMGR PPRDFEVRAQ VFGDHPLVFI APAGHPLAGV
     LEISRERIAR EQFLVREKGS GTRISLEIFL SDTPHELEEL GTEIASNETI KQAVIAGLGI
     AFISAHTIEQ EVKLGRLVIL DVIDTPIRRQ WFTVSRLDRA ATPAMQAFEQ FVLSSGARYL
     PVVSKPYPAN AFG