YFDC_ECOLI
ID YFDC_ECOLI Reviewed; 310 AA.
AC P37327;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=Inner membrane protein YfdC;
GN Name=yfdC; OrderedLocusNames=b2347, JW2344;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RA Baumann S.;
RL Submitted (JUN-1994) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT its sequence features.";
RL DNA Res. 4:91-113(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP IDENTIFICATION.
RA Rudd K.E.;
RL Unpublished observations (AUG-1994).
RN [6]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
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DR EMBL; U00096; AAC75407.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA16207.1; -; Genomic_DNA.
DR EMBL; U11296; -; NOT_ANNOTATED_CDS; Unassigned_DNA.
DR PIR; A65008; A65008.
DR RefSeq; NP_416849.1; NC_000913.3.
DR RefSeq; WP_000368140.1; NZ_LN832404.1.
DR AlphaFoldDB; P37327; -.
DR SMR; P37327; -.
DR BioGRID; 4260539; 8.
DR STRING; 511145.b2347; -.
DR TCDB; 1.A.16.4.1; the formate-nitrite transporter (fnt) family.
DR PaxDb; P37327; -.
DR PRIDE; P37327; -.
DR EnsemblBacteria; AAC75407; AAC75407; b2347.
DR EnsemblBacteria; BAA16207; BAA16207; BAA16207.
DR GeneID; 944801; -.
DR KEGG; ecj:JW2344; -.
DR KEGG; eco:b2347; -.
DR PATRIC; fig|1411691.4.peg.4385; -.
DR EchoBASE; EB2319; -.
DR eggNOG; COG2116; Bacteria.
DR HOGENOM; CLU_061519_1_0_6; -.
DR InParanoid; P37327; -.
DR OMA; GWMIATM; -.
DR PhylomeDB; P37327; -.
DR BioCyc; EcoCyc:G7217-MON; -.
DR PRO; PR:P37327; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; ISM:EcoCyc.
DR GO; GO:0015499; F:formate transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015724; P:formate transport; IBA:GO_Central.
DR Gene3D; 1.20.1080.10; -; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR000292; For/NO2_transpt.
DR PANTHER; PTHR30520; PTHR30520; 1.
DR Pfam; PF01226; Form_Nir_trans; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..310
FT /note="Inner membrane protein YfdC"
FT /id="PRO_0000169200"
FT TOPO_DOM 1..58
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 59..81
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 82..90
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 91..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 114..133
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..156
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 157..186
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 187..206
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 207..212
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 213..232
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 233..251
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 252..274
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 275..310
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 310 AA; 34503 MW; 96D34F450B209ED3 CRC64;
MDNDKIDQHS DEIEVESEEK ERGKKIEIDE DRLPSRAMAI HEHIRQDGEK ELERDAMALL
WSAIAAGLSM GASLLAKGIF QVELEGVPGS FLLENLGYTF GFIIVIMARQ QLFTENTVTA
VLPVMQKPTM SNVGLLIRLW GVVLLGNILG TGIAAWAFEY MPIFNEETRD AFVKIGMDVM
KNTPSEMFAN AIISGWLIAT MVWMFPAAGA AKIVVIILMT WLIALGDTTH IVVGSVEILY
LVFNGTLHWS DFIWPFALPT LAGNICGGTF IFALMSHAQI RNDMSNKRKA EARQKAERAE
NIKKNYKNPA
