YFEA_YERPE
ID YFEA_YERPE Reviewed; 311 AA.
AC Q56952; Q0WE85;
DT 01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 2.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Periplasmic chelated iron-binding protein YfeA;
DE Flags: Precursor;
GN Name=yfeA; OrderedLocusNames=YPO2439, y1897, YP_2227;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KIM6;
RX PubMed=9495751; DOI=10.1128/jb.180.5.1135-1147.1998;
RA Bearden S.W., Staggs T.M., Perry R.D.;
RT "An ABC transporter system of Yersinia pestis allows utilization of
RT chelated iron by Escherichia coli SAB11.";
RL J. Bacteriol. 180:1135-1147(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- FUNCTION: Part of an ATP-driven transport system YfeABCD for chelated
CC iron.
CC -!- SUBCELLULAR LOCATION: Periplasm.
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein 9 family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM85464.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=AAS62433.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAL21067.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U50597; AAC46147.1; -; Genomic_DNA.
DR EMBL; AL590842; CAL21067.1; ALT_INIT; Genomic_DNA.
DR EMBL; AE009952; AAM85464.1; ALT_INIT; Genomic_DNA.
DR EMBL; AE017042; AAS62433.1; ALT_INIT; Genomic_DNA.
DR PIR; AH0297; AH0297.
DR RefSeq; YP_002347403.1; NC_003143.1.
DR PDB; 5UXS; X-ray; 1.42 A; A=1-311.
DR PDB; 5UXU; X-ray; 1.84 A; A=1-311.
DR PDB; 5UY0; X-ray; 1.71 A; A=1-311.
DR PDB; 5UY4; X-ray; 1.92 A; A=1-311.
DR PDB; 5UY5; X-ray; 2.14 A; A=1-311.
DR PDB; 5UYA; X-ray; 1.72 A; A=1-311.
DR PDB; 5UYB; X-ray; 1.95 A; A=1-311.
DR PDB; 5UYC; X-ray; 1.96 A; A=1-311.
DR PDB; 5UYD; X-ray; 1.93 A; A=1-311.
DR PDB; 5UYE; X-ray; 2.09 A; A=1-311.
DR PDB; 5UYF; X-ray; 2.06 A; A=1-311.
DR PDB; 5UYG; X-ray; 1.86 A; A=1-311.
DR PDB; 5UYH; X-ray; 1.99 A; A=1-311.
DR PDB; 5UYV; X-ray; 1.69 A; A=1-311.
DR PDB; 5UYW; X-ray; 1.95 A; A=1-311.
DR PDB; 6Q1C; X-ray; 1.76 A; A=1-311.
DR PDB; 6Q1D; X-ray; 1.79 A; A=1-311.
DR PDB; 7ME1; X-ray; 2.05 A; A/B=1-311.
DR PDB; 7ME2; X-ray; 1.85 A; A/B=1-311.
DR PDB; 7ME3; X-ray; 2.25 A; A/B=1-311.
DR PDBsum; 5UXS; -.
DR PDBsum; 5UXU; -.
DR PDBsum; 5UY0; -.
DR PDBsum; 5UY4; -.
DR PDBsum; 5UY5; -.
DR PDBsum; 5UYA; -.
DR PDBsum; 5UYB; -.
DR PDBsum; 5UYC; -.
DR PDBsum; 5UYD; -.
DR PDBsum; 5UYE; -.
DR PDBsum; 5UYF; -.
DR PDBsum; 5UYG; -.
DR PDBsum; 5UYH; -.
DR PDBsum; 5UYV; -.
DR PDBsum; 5UYW; -.
DR PDBsum; 6Q1C; -.
DR PDBsum; 6Q1D; -.
DR PDBsum; 7ME1; -.
DR PDBsum; 7ME2; -.
DR PDBsum; 7ME3; -.
DR AlphaFoldDB; Q56952; -.
DR SMR; Q56952; -.
DR STRING; 214092.YPO2439; -.
DR TCDB; 3.A.1.15.4; the atp-binding cassette (abc) superfamily.
DR PaxDb; Q56952; -.
DR DNASU; 1146844; -.
DR EnsemblBacteria; AAM85464; AAM85464; y1897.
DR EnsemblBacteria; AAS62433; AAS62433; YP_2227.
DR KEGG; ype:YPO2439; -.
DR KEGG; ypk:y1897; -.
DR KEGG; ypm:YP_2227; -.
DR PATRIC; fig|214092.21.peg.2850; -.
DR eggNOG; COG0803; Bacteria.
DR HOGENOM; CLU_016838_1_1_6; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR GO; GO:0071281; P:cellular response to iron ion; EXP:CollecTF.
DR GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR GO; GO:0030001; P:metal ion transport; IEA:InterPro.
DR InterPro; IPR006129; AdhesinB.
DR InterPro; IPR006128; Lipoprotein_4.
DR InterPro; IPR006127; ZnuA-like.
DR Pfam; PF01297; ZnuA; 1.
DR PRINTS; PR00691; ADHESINB.
DR PRINTS; PR00690; ADHESNFAMILY.
PE 1: Evidence at protein level;
KW 3D-structure; Ion transport; Iron; Iron transport; Metal-binding;
KW Periplasm; Reference proteome; Signal; Transport.
FT SIGNAL 1..31
FT /evidence="ECO:0000255"
FT CHAIN 32..311
FT /note="Periplasmic chelated iron-binding protein YfeA"
FT /id="PRO_0000031873"
FT BINDING 76
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000250"
FT BINDING 141
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000250"
FT BINDING 207
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000250"
FT STRAND 42..48
FT /evidence="ECO:0007829|PDB:5UXS"
FT HELIX 49..59
FT /evidence="ECO:0007829|PDB:5UXS"
FT STRAND 62..69
FT /evidence="ECO:0007829|PDB:5UXS"
FT HELIX 82..89
FT /evidence="ECO:0007829|PDB:5UXS"
FT STRAND 92..96
FT /evidence="ECO:0007829|PDB:5UXS"
FT HELIX 105..109
FT /evidence="ECO:0007829|PDB:5UXS"
FT STRAND 117..119
FT /evidence="ECO:0007829|PDB:5UXS"
FT TURN 120..123
FT /evidence="ECO:0007829|PDB:5UXS"
FT TURN 133..136
FT /evidence="ECO:0007829|PDB:5UXS"
FT STRAND 137..139
FT /evidence="ECO:0007829|PDB:7ME3"
FT HELIX 142..144
FT /evidence="ECO:0007829|PDB:5UXS"
FT HELIX 146..163
FT /evidence="ECO:0007829|PDB:5UXS"
FT HELIX 165..167
FT /evidence="ECO:0007829|PDB:5UXS"
FT HELIX 168..194
FT /evidence="ECO:0007829|PDB:5UXS"
FT HELIX 198..200
FT /evidence="ECO:0007829|PDB:5UXS"
FT STRAND 202..208
FT /evidence="ECO:0007829|PDB:5UXS"
FT HELIX 211..217
FT /evidence="ECO:0007829|PDB:5UXS"
FT STRAND 220..230
FT /evidence="ECO:0007829|PDB:5UXS"
FT HELIX 237..248
FT /evidence="ECO:0007829|PDB:5UXS"
FT STRAND 252..256
FT /evidence="ECO:0007829|PDB:5UXS"
FT HELIX 262..270
FT /evidence="ECO:0007829|PDB:5UXS"
FT STRAND 274..279
FT /evidence="ECO:0007829|PDB:5UXS"
FT HELIX 294..308
FT /evidence="ECO:0007829|PDB:5UXS"
SQ SEQUENCE 311 AA; 34389 MW; 3C793D5B7BB45919 CRC64;
MIERLNSPFL RAAALFTIVA FSSLISTAAL AENNPSDTAK KFKVVTTFTI IQDIAQNIAG
DVAVVESITK PGAEIHDYQP TPRDIVKAQS ADLILWNGMN LERWFEKFFE SIKDVPSAVV
TAGITPLPIR EGPYSGIANP HAWMSPSNAL IYIENIRKAL VEHDPAHAET YNRNAQAYAE
KIKALDAPLR ERLSRIPAEQ RWLVTSEGAF SYLAKDYGFK EVYLWPINAE QQGIPQQVRH
VIDIIRENKI PVVFSESTIS DKPAKQVSKE TGAQYGGVLY VDSLSGEKGP VPTYISLINM
TVDTIAKGFG Q
