YFEB_YERPE
ID YFEB_YERPE Reviewed; 296 AA.
AC Q56953; Q0WE84;
DT 01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 149.
DE RecName: Full=Chelated iron transport system membrane protein YfeB;
GN Name=yfeB; OrderedLocusNames=YPO2440, y1896, YP_2228;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KIM6;
RX PubMed=9495751; DOI=10.1128/jb.180.5.1135-1147.1998;
RA Bearden S.W., Staggs T.M., Perry R.D.;
RT "An ABC transporter system of Yersinia pestis allows utilization of
RT chelated iron by Escherichia coli SAB11.";
RL J. Bacteriol. 180:1135-1147(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- FUNCTION: Part of an ATP-driven transport system YfeABCD for chelated
CC iron.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Peripheral
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; U50597; AAC46148.1; -; Genomic_DNA.
DR EMBL; AL590842; CAL21068.1; -; Genomic_DNA.
DR EMBL; AE009952; AAM85463.1; -; Genomic_DNA.
DR EMBL; AE017042; AAS62434.1; -; Genomic_DNA.
DR PIR; AI0297; AI0297.
DR RefSeq; WP_002211843.1; NZ_WUCM01000025.1.
DR RefSeq; YP_002347404.1; NC_003143.1.
DR AlphaFoldDB; Q56953; -.
DR SMR; Q56953; -.
DR STRING; 214092.YPO2440; -.
DR TCDB; 3.A.1.15.4; the atp-binding cassette (abc) superfamily.
DR PaxDb; Q56953; -.
DR DNASU; 1146843; -.
DR EnsemblBacteria; AAM85463; AAM85463; y1896.
DR EnsemblBacteria; AAS62434; AAS62434; YP_2228.
DR GeneID; 66841220; -.
DR KEGG; ype:YPO2440; -.
DR KEGG; ypk:y1896; -.
DR KEGG; ypm:YP_2228; -.
DR PATRIC; fig|214092.21.peg.2851; -.
DR eggNOG; COG1121; Bacteria.
DR HOGENOM; CLU_000604_1_11_6; -.
DR OMA; SVWDVVM; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0071281; P:cellular response to iron ion; EXP:CollecTF.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Ion transport; Iron;
KW Iron transport; Membrane; Nucleotide-binding; Reference proteome;
KW Transport.
FT CHAIN 1..296
FT /note="Chelated iron transport system membrane protein
FT YfeB"
FT /id="PRO_0000093126"
FT DOMAIN 11..246
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT REGION 276..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 44..51
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 296 AA; 32396 MW; DDCCF5099856D756 CRC64;
MSHPVFVRPE LVVDNVTVTY NNGHTAIYDA SFSLTGGTIC ALVGVNGSGK STLFKSIMGL
VKPSVGKVEL SHKPISHALK QNTIAYVPQT EDVDWNFPVL VEDVVMMGRY GKMNFLRIPS
REDKAIVNKS IERVGLTALR SRQIGELSGG QKKRVFLARA LAQQGTLLLL DEPFTGVDVK
TENAIIELLQ SLRDEGHLIL VSTHNLGSVP EFCDHVILIN QTVLAAGPIE TTFTQKNLEM
TFGGVLRHIN LSGTALHDDN DPRTVTVITD DERPAVFYGH TKNDPPAQSQ SKEQNS
