YFED_YERPE
ID YFED_YERPE Reviewed; 297 AA.
AC Q56955; Q0WE82;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 16-NOV-2001, sequence version 2.
DT 25-MAY-2022, entry version 146.
DE RecName: Full=Chelated iron transport system membrane protein YfeD;
GN Name=yfeD; OrderedLocusNames=YPO2442, y1894, YP_2230;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KIM6;
RX PubMed=9495751; DOI=10.1128/jb.180.5.1135-1147.1998;
RA Bearden S.W., Staggs T.M., Perry R.D.;
RT "An ABC transporter system of Yersinia pestis allows utilization of
RT chelated iron by Escherichia coli SAB11.";
RL J. Bacteriol. 180:1135-1147(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- FUNCTION: Part of an ATP-driven transport system YfeABCD for chelated
CC iron.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ABC-3 integral membrane protein family.
CC {ECO:0000305}.
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DR EMBL; U50597; AAC46150.1; -; Genomic_DNA.
DR EMBL; AL590842; CAL21070.1; -; Genomic_DNA.
DR EMBL; AE009952; AAM85461.1; -; Genomic_DNA.
DR EMBL; AE017042; AAS62436.1; -; Genomic_DNA.
DR PIR; AC0298; AC0298.
DR RefSeq; WP_002211845.1; NZ_WUCM01000025.1.
DR RefSeq; YP_002347406.1; NC_003143.1.
DR AlphaFoldDB; Q56955; -.
DR SMR; Q56955; -.
DR STRING; 214092.YPO2442; -.
DR TCDB; 3.A.1.15.4; the atp-binding cassette (abc) superfamily.
DR PaxDb; Q56955; -.
DR DNASU; 1146841; -.
DR EnsemblBacteria; AAM85461; AAM85461; y1894.
DR EnsemblBacteria; AAS62436; AAS62436; YP_2230.
DR GeneID; 66841218; -.
DR KEGG; ype:YPO2442; -.
DR KEGG; ypk:y1894; -.
DR KEGG; ypm:YP_2230; -.
DR PATRIC; fig|1028802.3.peg.469; -.
DR eggNOG; COG1108; Bacteria.
DR HOGENOM; CLU_028808_4_0_6; -.
DR OMA; CALLSCW; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0071281; P:cellular response to iron ion; EXP:CollecTF.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR GO; GO:0010043; P:response to zinc ion; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.3470.10; -; 1.
DR InterPro; IPR037294; ABC_BtuC-like.
DR InterPro; IPR001626; ABC_TroCD.
DR PANTHER; PTHR30477; PTHR30477; 1.
DR Pfam; PF00950; ABC-3; 1.
DR SUPFAM; SSF81345; SSF81345; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Iron; Iron transport;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..297
FT /note="Chelated iron transport system membrane protein
FT YfeD"
FT /id="PRO_0000171157"
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..78
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 197..217
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 248..268
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 185
FT /note="C -> S (in Ref. 1; AAC46150)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 297 AA; 32203 MW; 31329E7877863779 CRC64;
MNMLFSLISE PFAYPFMQRA IVAAIVTGVV CAILSCYLVL KGWSLMGDAI SHAVLPGIVL
AFWLGIPLVI GAFVSGIFCA VATGYLKENS RVKEDTVMGI VFSGMFAFGL VLFSRIDTDQ
HLSHILFGNM LGISLTELKQ TLWIAGFTLL VVLLKRKDFM LYCFDPNHAR VIGLPVKFLH
YGLLCLLALT IVASLQAVGV ILVIAMLIAP GIIAFMICRS FDQMLVVATL VSVVACVLGT
LISFHIDGAT GPCIVIIQAL FFVVALIYNH IKPIKDRKMA PLTKAVNPEN TAPSNLP
