ID   YFEH_ECOLI              Reviewed;         332 AA.
AC   P39836; P76532; P76958;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=Putative symporter YfeH;
GN   Name=yfeH; OrderedLocusNames=b2410, JW5876;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA   Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA   Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA   Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA   Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT   "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT   genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT   its sequence features.";
RL   DNA Res. 4:91-113(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 94-332.
RA   O'Connor M.J., Ally A., Ally D., Zhang X., Robichaud M., Backman K.;
RL   Submitted (APR-1989) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   IDENTIFICATION.
RX   PubMed=7984428; DOI=10.1093/nar/22.22.4756;
RA   Borodovsky M., Rudd K.E., Koonin E.V.;
RT   "Intrinsic and extrinsic approaches for detecting genes in a bacterial
RT   genome.";
RL   Nucleic Acids Res. 22:4756-4767(1994).
CC   -!- SIMILARITY: Belongs to the bile acid:sodium symporter (BASS) (TC
CC       2.A.28) family. {ECO:0000305}.
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DR   EMBL; U00096; AAC75463.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA16281.2; -; Genomic_DNA.
DR   EMBL; M24278; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; A65015; A65015.
DR   RefSeq; NP_416905.1; NC_000913.3.
DR   RefSeq; WP_000765610.1; NZ_LN832404.1.
DR   AlphaFoldDB; P39836; -.
DR   SMR; P39836; -.
DR   BioGRID; 4259668; 228.
DR   STRING; 511145.b2410; -.
DR   TCDB; 2.A.28.3.4; the bile acid:na(+) symporter (bass) family.
DR   PaxDb; P39836; -.
DR   PRIDE; P39836; -.
DR   DNASU; 946874; -.
DR   EnsemblBacteria; AAC75463; AAC75463; b2410.
DR   EnsemblBacteria; BAA16281; BAA16281; BAA16281.
DR   GeneID; 946874; -.
DR   KEGG; ecj:JW5876; -.
DR   KEGG; eco:b2410; -.
DR   PATRIC; fig|1411691.4.peg.4322; -.
DR   EchoBASE; EB2279; -.
DR   eggNOG; COG0385; Bacteria.
DR   HOGENOM; CLU_039013_1_0_6; -.
DR   InParanoid; P39836; -.
DR   OMA; IYQRVFM; -.
DR   PhylomeDB; P39836; -.
DR   BioCyc; EcoCyc:EG12376-MON; -.
DR   PRO; PR:P39836; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   InterPro; IPR016833; Put_Na-Bile_cotransptr.
DR   PANTHER; PTHR18640; PTHR18640; 1.
DR   Pfam; PF13593; SBF_like; 1.
DR   PIRSF; PIRSF026166; UCP026166; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Symport; Transport.
FT   CHAIN           1..332
FT                   /note="Putative symporter YfeH"
FT                   /id="PRO_0000169221"
FT   CONFLICT        325..332
FT                   /note="QESSADKA -> RKAAPIKLKADASGAGPVASAPRF (in Ref. 4;
FT                   M24278)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   332 AA;  36406 MW;  B8C96697C5BC3CF1 CRC64;
     MKLFRILDPF TLTLITVVLL ASFFPARGDF VPFFENLTTA AIALLFFMHG AKLSREAIIA
     GGGHWRLHLW VMCSTFVLFP ILGVLFAWWK PVNVDPMLYS GFLYLCILPA TVQSAIAFTS
     MAGGNVAAAV CSASASSLLG IFLSPLLVGL VMNVHGAGGS LEQVGKIMLQ LLLPFVLGHL
     SRPWIGDWVS RNKKWIAKTD QTSILLVVYT AFSEAVVNGI WHKVGWGSLL FIVVVSCVLL
     AIVIVVNVFM ARRLSFNKAD EITIVFCGSK KSLANGIPMA NILFPTSVIG MMVLPLMIFH
     QIQLMVCAVL ARRYKRQTEQ LQAQQESSAD KA