ID   YFEO_ECOL5              Reviewed;         418 AA.
AC   Q0TF71;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Putative ion-transport protein YfeO {ECO:0000255|HAMAP-Rule:MF_01115};
GN   Name=yfeO {ECO:0000255|HAMAP-Rule:MF_01115}; OrderedLocusNames=ECP_2415;
OS   Escherichia coli O6:K15:H31 (strain 536 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=362663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=536 / UPEC;
RX   PubMed=16879640; DOI=10.1111/j.1365-2958.2006.05255.x;
RA   Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U.,
RA   Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.;
RT   "Role of pathogenicity island-associated integrases in the genome
RT   plasticity of uropathogenic Escherichia coli strain 536.";
RL   Mol. Microbiol. 61:584-595(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01115};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01115}.
CC   -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01115}.
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DR   EMBL; CP000247; ABG70408.1; -; Genomic_DNA.
DR   RefSeq; WP_000903097.1; NC_008253.1.
DR   AlphaFoldDB; Q0TF71; -.
DR   SMR; Q0TF71; -.
DR   STRING; 362663.ECP_2415; -.
DR   EnsemblBacteria; ABG70408; ABG70408; ECP_2415.
DR   KEGG; ecp:ECP_2415; -.
DR   HOGENOM; CLU_053130_0_0_6; -.
DR   OMA; WKVPGHA; -.
DR   Proteomes; UP000009182; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   HAMAP; MF_01115; CLC_YfeO; 1.
DR   InterPro; IPR022969; Chloride_channel_YfeO.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   PRINTS; PR00762; CLCHANNEL.
DR   SUPFAM; SSF81340; SSF81340; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion channel; Ion transport; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..418
FT                   /note="Putative ion-transport protein YfeO"
FT                   /id="PRO_0000298432"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        223..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        258..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        300..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        322..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        371..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
SQ   SEQUENCE   418 AA;  43588 MW;  22B74EF5797AEBD2 CRC64;
     MLHPRARTML LLSLPAVAIG IASSLILIMV MKIASVLQNL LWQRLPGTLG IAQDSPLWII
     GVLTLTGIAV GLVIRFSQGH AGPDPACEPL IGAPVPPSAL PGLIVALILG LAGGVSLGPE
     HPIITVNIAL AVAIGARLLP RVNRMEWTIL ASAGTIGALF GTPVAAALIF SQTLNGSNEV
     PLWDRLFAPL MAAAAGALTT GLFFHPHFSL PIAHYGQMEM TDILSGAIVA AIAIAAGMVA
     VWCLPRLHAM MHQMKNPVFV LGIGGLILGI LGVIGGPVSL FKGLDEMQQM VANQAFSTSG
     YFLLAVIKLA ALVVAAASGF RGGRIFPAVF VGVALGLMLH EHVPAVPAAI TVSCAILGIV
     LVVTRDGWLS LFMAAVVVPN TTLLPLLCIV MLPAWLLLAG KPMMMVNRQK QQPPHDNV