ID   YFEO_SALPA              Reviewed;         411 AA.
AC   Q5PNE6;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Putative ion-transport protein YfeO {ECO:0000255|HAMAP-Rule:MF_01115};
GN   Name=yfeO {ECO:0000255|HAMAP-Rule:MF_01115}; OrderedLocusNames=SPA0456;
OS   Salmonella paratyphi A (strain ATCC 9150 / SARB42).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=295319;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 9150 / SARB42;
RX   PubMed=15531882; DOI=10.1038/ng1470;
RA   McClelland M., Sanderson K.E., Clifton S.W., Latreille P., Porwollik S.,
RA   Sabo A., Meyer R., Bieri T., Ozersky P., McLellan M., Harkins C.R.,
RA   Wang C., Nguyen C., Berghoff A., Elliott G., Kohlberg S., Strong C., Du F.,
RA   Carter J., Kremizki C., Layman D., Leonard S., Sun H., Fulton L., Nash W.,
RA   Miner T., Minx P., Delehaunty K., Fronick C., Magrini V., Nhan M.,
RA   Warren W., Florea L., Spieth J., Wilson R.K.;
RT   "Comparison of genome degradation in Paratyphi A and Typhi, human-
RT   restricted serovars of Salmonella enterica that cause typhoid.";
RL   Nat. Genet. 36:1268-1274(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01115};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01115}.
CC   -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01115}.
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DR   EMBL; CP000026; AAV76461.1; -; Genomic_DNA.
DR   RefSeq; WP_000468912.1; NC_006511.1.
DR   AlphaFoldDB; Q5PNE6; -.
DR   SMR; Q5PNE6; -.
DR   EnsemblBacteria; AAV76461; AAV76461; SPA0456.
DR   KEGG; spt:SPA0456; -.
DR   HOGENOM; CLU_053130_0_0_6; -.
DR   OMA; WKVPGHA; -.
DR   Proteomes; UP000008185; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   HAMAP; MF_01115; CLC_YfeO; 1.
DR   InterPro; IPR022969; Chloride_channel_YfeO.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   PRINTS; PR00762; CLCHANNEL.
DR   SUPFAM; SSF81340; SSF81340; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion channel; Ion transport; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..411
FT                   /note="Putative ion-transport protein YfeO"
FT                   /id="PRO_0000298434"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        223..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        258..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        296..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        322..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        386..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
SQ   SEQUENCE   411 AA;  42968 MW;  AE29411281CCAB4C CRC64;
     MFHPRARTML LLSLPALIIG VASSLVLIAA MKIASVFQQF LWQRLPASIG IAYDSPFWIV
     GMLTLTGIVV GLIIRYSPGH AGPDPAIEPL ISMPVSPSAL PGLLLALIIG LAGGVSLGPE
     HPIMTINIAL AAAFGSRLFP RITALDWTIL ASAGTIGALF GTPVAAALIF SQTLSGSNDI
     PMWDRLFAPL MAAAAGSLTT SLFFHPHFSL PIAHYTQMRL VDIASGAIVA AIAIAAGMVA
     VWCLPRLHEL LHRLKNPVLI LGIGGFILGI LGVIGGPLTL FKGLDEMQQM AFSQTLGAGD
     YFTLAVVKLA ALVIAAASGF RGGRIFPAVF IGAALGLMLH AHVEAVPAAI TVSCAILGLV
     LVVTRDGWLS LFMAAVVVPD TNLLPLLCIV MLPAWLLLAG KPLLAANRHE P