ID   YFEO_SALTI              Reviewed;         411 AA.
AC   Q8Z4X8;
DT   11-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Putative ion-transport protein YfeO;
GN   Name=yfeO; OrderedLocusNames=STY2645, t0453;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC       {ECO:0000305}.
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DR   EMBL; AL513382; CAD07642.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO68165.1; -; Genomic_DNA.
DR   RefSeq; NP_456947.1; NC_003198.1.
DR   RefSeq; WP_000468932.1; NZ_WSUR01000025.1.
DR   AlphaFoldDB; Q8Z4X8; -.
DR   SMR; Q8Z4X8; -.
DR   STRING; 220341.16503629; -.
DR   EnsemblBacteria; AAO68165; AAO68165; t0453.
DR   KEGG; stt:t0453; -.
DR   KEGG; sty:STY2645; -.
DR   PATRIC; fig|220341.7.peg.2681; -.
DR   eggNOG; COG0038; Bacteria.
DR   HOGENOM; CLU_053130_0_0_6; -.
DR   OMA; WKVPGHA; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   HAMAP; MF_01115; CLC_YfeO; 1.
DR   InterPro; IPR022969; Chloride_channel_YfeO.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   PRINTS; PR00762; CLCHANNEL.
DR   SUPFAM; SSF81340; SSF81340; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion channel; Ion transport; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..411
FT                   /note="Putative ion-transport protein YfeO"
FT                   /id="PRO_0000094497"
FT   TRANSMEM        9..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        223..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        258..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        295..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        322..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        345..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        376..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   411 AA;  42970 MW;  FAE0F3A587BE1705 CRC64;
     MFHPRARTML LLSLPALIIG VASSLVLIAS MKVASVFQQF LWQRLPASIG IAYDSPFWIV
     GMLTLTGIVV GLIIRYSPGH AGPDPAIEPL ISMPVSPSAL PGLLLALIIG LAGGVSLGPE
     HPIMTINIAL AAAFGSRLFP RITALDWTIL ASAGTIGALF GTPVAAALIF SQTLSGSNDI
     PMWDRLFAPL MAAAAGSLTT SLFFHPHFSL PIAHYTQMRL VDIASGAIVA AIAIAAGMVA
     VWCLPRLHEL LHRLKNPVLI LGIGGFILGI LGVIGGPLTL FKGLDEMQQM AFSQTLGAGD
     YFTLAVVKLA ALVIAAASGF RGGRIFPAVF IGAALGLMLH AHVEAVPAAI TVSCAILGLV
     LVVTRDGWLS LFMAAVVVPD TNLLPLLCIV MLPAWLLLAG KPLLAANRHE P