ID   YFEO_SHIF8              Reviewed;         418 AA.
AC   Q0T2B0;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Putative ion-transport protein YfeO {ECO:0000255|HAMAP-Rule:MF_01115};
GN   Name=yfeO {ECO:0000255|HAMAP-Rule:MF_01115}; OrderedLocusNames=SFV_2447;
OS   Shigella flexneri serotype 5b (strain 8401).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=373384;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=8401;
RX   PubMed=16822325; DOI=10.1186/1471-2164-7-173;
RA   Nie H., Yang F., Zhang X., Yang J., Chen L., Wang J., Xiong Z., Peng J.,
RA   Sun L., Dong J., Xue Y., Xu X., Chen S., Yao Z., Shen Y., Jin Q.;
RT   "Complete genome sequence of Shigella flexneri 5b and comparison with
RT   Shigella flexneri 2a.";
RL   BMC Genomics 7:173-173(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01115};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01115}.
CC   -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01115}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000266; ABF04555.1; -; Genomic_DNA.
DR   RefSeq; WP_000903152.1; NC_008258.1.
DR   AlphaFoldDB; Q0T2B0; -.
DR   SMR; Q0T2B0; -.
DR   EnsemblBacteria; ABF04555; ABF04555; SFV_2447.
DR   GeneID; 58389603; -.
DR   KEGG; sfv:SFV_2447; -.
DR   HOGENOM; CLU_053130_0_0_6; -.
DR   OMA; WKVPGHA; -.
DR   BioCyc; SFLE373384:SFV_RS13620-MON; -.
DR   Proteomes; UP000000659; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   HAMAP; MF_01115; CLC_YfeO; 1.
DR   InterPro; IPR022969; Chloride_channel_YfeO.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   PRINTS; PR00762; CLCHANNEL.
DR   SUPFAM; SSF81340; SSF81340; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion channel; Ion transport; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..418
FT                   /note="Putative ion-transport protein YfeO"
FT                   /id="PRO_0000298436"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        223..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        258..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        300..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        322..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
FT   TRANSMEM        371..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01115"
SQ   SEQUENCE   418 AA;  43551 MW;  0461D0F16514890F CRC64;
     MLHPRARTML LLSLPAVAIG IASSLILIVV MKIASVLQNL LWQRLPGTLG IAQDSPLWII
     GVLTLTGIAV GLVIRFSQGH AGPDPACEPL IGAPVPPSAL PGLIVALILG LAGGVSLGPE
     HPIMTVNIAL AVAIGARLLP RVNRMEWTIL ASAGTIGALF GTPVAAALIF SQTLNGSSEV
     PLWDRLFAPL MAAAAGALTT GLFFHPHFSL PIAHYGQMEM TDILSGAIVA AIAIAAGMVA
     VWCLPRLHAM MNQMKNPVLV LGIGGFILGI LGVIGGPVSL FKGLDEMQQM VANQAFSTSD
     YFLLAVIKLA ALVVAAASGF RGGRIFPAVF VGVALGLMLH EHVPAVPAAI TVSCAILGIV
     LVVTRDGWLS LFMAAVVVPN TTLLPLLCIV MLPAWLLLAG KPMMMVNRPK QQPPHDNV