YFER_ECOLI
ID YFER_ECOLI Reviewed; 308 AA.
AC P0ACR7; P77500;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Uncharacterized HTH-type transcriptional regulator YfeR;
GN Name=yfeR; OrderedLocusNames=b2409, JW2400;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT its sequence features.";
RL DNA Res. 4:91-113(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U00096; AAC75462.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA16280.1; -; Genomic_DNA.
DR PIR; H65014; H65014.
DR RefSeq; NP_416904.1; NC_000913.3.
DR RefSeq; WP_001109794.1; NZ_STEB01000039.1.
DR AlphaFoldDB; P0ACR7; -.
DR SMR; P0ACR7; -.
DR BioGRID; 4261239; 25.
DR BioGRID; 851213; 1.
DR DIP; DIP-12017N; -.
DR IntAct; P0ACR7; 2.
DR STRING; 511145.b2409; -.
DR PaxDb; P0ACR7; -.
DR PRIDE; P0ACR7; -.
DR EnsemblBacteria; AAC75462; AAC75462; b2409.
DR EnsemblBacteria; BAA16280; BAA16280; BAA16280.
DR GeneID; 66673721; -.
DR GeneID; 946873; -.
DR KEGG; ecj:JW2400; -.
DR KEGG; eco:b2409; -.
DR PATRIC; fig|1411691.4.peg.4323; -.
DR EchoBASE; EB3911; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_0_6; -.
DR InParanoid; P0ACR7; -.
DR OMA; CRRDHEL; -.
DR PhylomeDB; P0ACR7; -.
DR BioCyc; EcoCyc:G7257-MON; -.
DR PRO; PR:P0ACR7; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..308
FT /note="Uncharacterized HTH-type transcriptional regulator
FT YfeR"
FT /id="PRO_0000105791"
FT DOMAIN 1..60
FT /note="HTH lysR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT DNA_BIND 20..39
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ SEQUENCE 308 AA; 33903 MW; 23B6A771E4AB8587 CRC64;
MNYSLKQLKV FVTVAQEKSF SRAGERIGLS QSAVSHSVKE LENHTGVRLL DRTTREVVLT
DAGQQLALRL ERLLDELNST LRDTGRMGQQ LSGKVRVAAS QTISAHLIPQ CIAESHRRYP
DIQFVLHDRP QQWVMESIRQ GDVDFGIVID PGPVGDLQCE AILSEPFFLL CHRDSALAVE
DYVPWQALQG AKLVLQDYAS GSRPLIDAAL ARNGIQANIV QEIGHPATLF PMVAAGIGIS
ILPALALPLP EGSPLVVKRI TPVVERQLML VRRKNRSLST AAEALWDVVR DQGNALMAGR
EGDPLYQI
