YFER_SHIFL
ID YFER_SHIFL Reviewed; 308 AA.
AC P0ACR8; P77500;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 25-MAY-2022, entry version 109.
DE RecName: Full=Uncharacterized HTH-type transcriptional regulator YfeR;
GN Name=yfeR; OrderedLocusNames=SF2464, S2610;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE005674; AAN43971.1; -; Genomic_DNA.
DR EMBL; AE014073; AAP17784.1; -; Genomic_DNA.
DR RefSeq; NP_708264.1; NC_004337.2.
DR RefSeq; WP_001109794.1; NZ_WPGW01000027.1.
DR AlphaFoldDB; P0ACR8; -.
DR SMR; P0ACR8; -.
DR STRING; 198214.SF2464; -.
DR EnsemblBacteria; AAN43971; AAN43971; SF2464.
DR EnsemblBacteria; AAP17784; AAP17784; S2610.
DR GeneID; 1026769; -.
DR GeneID; 66673721; -.
DR KEGG; sfl:SF2464; -.
DR KEGG; sfx:S2610; -.
DR PATRIC; fig|198214.7.peg.2944; -.
DR HOGENOM; CLU_039613_6_0_6; -.
DR OMA; ERSIVMV; -.
DR OrthoDB; 990666at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..308
FT /note="Uncharacterized HTH-type transcriptional regulator
FT YfeR"
FT /id="PRO_0000105792"
FT DOMAIN 1..60
FT /note="HTH lysR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT DNA_BIND 20..39
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ SEQUENCE 308 AA; 33903 MW; 23B6A771E4AB8587 CRC64;
MNYSLKQLKV FVTVAQEKSF SRAGERIGLS QSAVSHSVKE LENHTGVRLL DRTTREVVLT
DAGQQLALRL ERLLDELNST LRDTGRMGQQ LSGKVRVAAS QTISAHLIPQ CIAESHRRYP
DIQFVLHDRP QQWVMESIRQ GDVDFGIVID PGPVGDLQCE AILSEPFFLL CHRDSALAVE
DYVPWQALQG AKLVLQDYAS GSRPLIDAAL ARNGIQANIV QEIGHPATLF PMVAAGIGIS
ILPALALPLP EGSPLVVKRI TPVVERQLML VRRKNRSLST AAEALWDVVR DQGNALMAGR
EGDPLYQI
