ID   YFEZ_ECOLI              Reviewed;         149 AA.
AC   P76538; Q2MAJ3;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 2.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Inner membrane protein YfeZ;
GN   Name=yfeZ; OrderedLocusNames=b2433, JW2426;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [3]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=15919996; DOI=10.1126/science.1109730;
RA   Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT   "Global topology analysis of the Escherichia coli inner membrane
RT   proteome.";
RL   Science 308:1321-1323(2005).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
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DR   EMBL; U00096; AAC75486.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76713.1; -; Genomic_DNA.
DR   PIR; H65017; H65017.
DR   RefSeq; NP_416928.4; NC_000913.3.
DR   RefSeq; WP_001350539.1; NZ_LN832404.1.
DR   AlphaFoldDB; P76538; -.
DR   BioGRID; 4260753; 13.
DR   DIP; DIP-12023N; -.
DR   IntAct; P76538; 4.
DR   STRING; 511145.b2433; -.
DR   TCDB; 9.B.127.1.1; the duf2919 (pf11143) family.
DR   PaxDb; P76538; -.
DR   PRIDE; P76538; -.
DR   EnsemblBacteria; AAC75486; AAC75486; b2433.
DR   EnsemblBacteria; BAE76713; BAE76713; BAE76713.
DR   GeneID; 946918; -.
DR   KEGG; ecj:JW2426; -.
DR   KEGG; eco:b2433; -.
DR   PATRIC; fig|1411691.4.peg.4298; -.
DR   EchoBASE; EB3919; -.
DR   eggNOG; ENOG5032RZ4; Bacteria.
DR   HOGENOM; CLU_115420_1_0_6; -.
DR   OMA; CWQPVLW; -.
DR   PhylomeDB; P76538; -.
DR   BioCyc; EcoCyc:G7268-MON; -.
DR   PRO; PR:P76538; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   InterPro; IPR021318; DUF2919.
DR   Pfam; PF11143; DUF2919; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..149
FT                   /note="Inner membrane protein YfeZ"
FT                   /id="PRO_0000169226"
FT   TOPO_DOM        1..18
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        40..58
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        80..89
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        111..115
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        137..149
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   149 AA;  17168 MW;  7FF61FD11F653DA5 CRC64;
     MKSTEFHPVH YDAHGRLRLP LLFWLVLLLQ ARTWVLFVIA GASREQGTAL LNLFYPDHDN
     FWLGLIPGIP AVLAFLLSGR RATFPRTWRV LYFLLLLAQV VLLCWQPWLW LNGESVSGIG
     LALVVADIVA LIWLLTNRRL RACFYEVKE