YFF1_YEAST
ID YFF1_YEAST Reviewed; 160 AA.
AC P43552; D6VTH9;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 143.
DE RecName: Full=Uncharacterized membrane protein YFL051C;
DE Flags: Precursor;
GN OrderedLocusNames=YFL051C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7670463; DOI=10.1038/ng0795-261;
RA Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S.,
RA Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H.,
RA Eki T.;
RT "Analysis of the nucleotide sequence of chromosome VI from Saccharomyces
RT cerevisiae.";
RL Nat. Genet. 10:261-268(1995).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 208353 / W303-1A;
RX PubMed=16847258; DOI=10.1073/pnas.0604075103;
RA Kim H., Melen K., Oesterberg M., von Heijne G.;
RT "A global topology map of the Saccharomyces cerevisiae membrane proteome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006).
CC -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein.
CC -!- SIMILARITY: To yeast protein FLO1. {ECO:0000305}.
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DR EMBL; D50617; BAA09190.1; -; Genomic_DNA.
DR EMBL; AY558469; AAS56795.1; -; Genomic_DNA.
DR EMBL; BK006940; DAA12389.1; -; Genomic_DNA.
DR PIR; S56204; S56204.
DR RefSeq; NP_116576.1; NM_001179916.1.
DR AlphaFoldDB; P43552; -.
DR SMR; P43552; -.
DR BioGRID; 31096; 77.
DR DIP; DIP-4270N; -.
DR IntAct; P43552; 1.
DR STRING; 4932.YFL051C; -.
DR PaxDb; P43552; -.
DR EnsemblFungi; YFL051C_mRNA; YFL051C; YFL051C.
DR GeneID; 850493; -.
DR KEGG; sce:YFL051C; -.
DR SGD; S000001843; YFL051C.
DR VEuPathDB; FungiDB:YFL051C; -.
DR GeneTree; ENSGT00940000180757; -.
DR HOGENOM; CLU_1590435_0_0_1; -.
DR BioCyc; YEAST:G3O-30414-MON; -.
DR PRO; PR:P43552; -.
DR Proteomes; UP000002311; Chromosome VI.
DR RNAct; P43552; protein.
DR GO; GO:0071944; C:cell periphery; HDA:SGD.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Cell membrane; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..160
FT /note="Uncharacterized membrane protein YFL051C"
FT /id="PRO_0000014318"
FT TOPO_DOM 24..132
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..155
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 156..160
FT /note="Extracellular"
FT /evidence="ECO:0000255"
SQ SEQUENCE 160 AA; 18110 MW; CDA512435B6005B1 CRC64;
MSIPHSVFSA LLVFVALATT TLASTEACLP TNKREDGMNI NFYEYTIGDQ TTYLEPEYMG
YEYSNTKKLG SVSGQTNLSI YYSPPCESTP TCVTYAVLKR DEDGYDPCGP LYETKKRDTE
YCDPNTAYWS SDLFGFYTTP TNVTVEMTGY LIWSMGNRRR
