ID   YFGM_HAEIN              Reviewed;         204 AA.
AC   P43989;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Ancillary SecYEG translocon subunit {ECO:0000250|UniProtKB:P76576};
DE   AltName: Full=Periplasmic chaperone YfgM {ECO:0000250|UniProtKB:P76576};
GN   OrderedLocusNames=HI_0370;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=10675023;
RX   DOI=10.1002/(sici)1522-2683(20000101)21:2<411::aid-elps411>3.0.co;2-4;
RA   Langen H., Takacs B., Evers S., Berndt P., Lahm H.W., Wipf B., Gray C.,
RA   Fountoulakis M.;
RT   "Two-dimensional map of the proteome of Haemophilus influenzae.";
RL   Electrophoresis 21:411-429(2000).
CC   -!- FUNCTION: May mediate protein transfer from the SecYEG translocon to
CC       the periplasmic chaperone network via its periplasmic C-terminal
CC       region. {ECO:0000250|UniProtKB:P76576}.
CC   -!- SUBUNIT: Interacts with the SecYEG translocon (By similarity). Forms a
CC       complex with PpiD (By similarity). {ECO:0000250|UniProtKB:P76576}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000250|UniProtKB:P76576}; Single-pass type II membrane protein
CC       {ECO:0000250|UniProtKB:P76576}; Periplasmic side
CC       {ECO:0000250|UniProtKB:P76576}.
CC   -!- SIMILARITY: Belongs to the YfgM family. {ECO:0000305}.
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DR   EMBL; L42023; AAC22028.1; -; Genomic_DNA.
DR   PIR; G64006; G64006.
DR   RefSeq; NP_438531.1; NC_000907.1.
DR   RefSeq; WP_005693794.1; NC_000907.1.
DR   AlphaFoldDB; P43989; -.
DR   SMR; P43989; -.
DR   STRING; 71421.HI_0370; -.
DR   EnsemblBacteria; AAC22028; AAC22028; HI_0370.
DR   KEGG; hin:HI_0370; -.
DR   PATRIC; fig|71421.8.peg.388; -.
DR   eggNOG; COG2976; Bacteria.
DR   HOGENOM; CLU_084785_0_0_6; -.
DR   OMA; RFFANNG; -.
DR   PhylomeDB; P43989; -.
DR   BioCyc; HINF71421:G1GJ1-383-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0071575; C:integral component of external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0032991; C:protein-containing complex; IBA:GO_Central.
DR   GO; GO:0044877; F:protein-containing complex binding; IEA:InterPro.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR018704; TPR_21.
DR   InterPro; IPR026039; YfgM.
DR   PANTHER; PTHR38035; PTHR38035; 1.
DR   Pfam; PF09976; TPR_21; 1.
DR   PIRSF; PIRSF006170; YfgM; 1.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Chaperone; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..204
FT                   /note="Ancillary SecYEG translocon subunit"
FT                   /id="PRO_0000214365"
FT   TOPO_DOM        1..23
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:P76576"
FT   TRANSMEM        24..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        43..204
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:P76576"
SQ   SEQUENCE   204 AA;  22664 MW;  D763A17EF99AA97A CRC64;
     MAYSIEEEQE INQLKDWWKE NGKTIIVAFI LGVGGMFGWR YWQTHQAEQI AQASAQYDTL
     INSVQQDEQA KKANIEQFVQ ANSKTAYAVF ALLDEAKKAT EKQDFSAAEA NLNQALTQSQ
     DEVLTSIVAL RLSAVQFQLG QLDNALSTLN QVKGESFNAR KAILTGDIQV AKGDKVAAKN
     SFEQAQQSGS QLEQQMAKMK LNNL