ID   YFH7_KLULA              Reviewed;         353 AA.
AC   Q6CNA8;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=ATP-dependent kinase YFH7;
DE            EC=2.7.1.-;
GN   Name=YFH7; OrderedLocusNames=KLLA0E13971g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: ATP-dependent kinase that could be involved in endoplasmic
CC       reticulum membrane assembly. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the YFH7 family. {ECO:0000305}.
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DR   EMBL; CR382125; CAG99668.1; -; Genomic_DNA.
DR   RefSeq; XP_454581.1; XM_454581.1.
DR   AlphaFoldDB; Q6CNA8; -.
DR   SMR; Q6CNA8; -.
DR   STRING; 28985.XP_454581.1; -.
DR   EnsemblFungi; CAG99668; CAG99668; KLLA0_E13971g.
DR   GeneID; 2893648; -.
DR   KEGG; kla:KLLA0_E13971g; -.
DR   eggNOG; KOG2702; Eukaryota.
DR   HOGENOM; CLU_067202_1_0_1; -.
DR   InParanoid; Q6CNA8; -.
DR   OMA; LYDQENW; -.
DR   Proteomes; UP000000598; Chromosome E.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:EnsemblFungi.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Kinase; Nucleotide-binding; Reference proteome; Transferase.
FT   CHAIN           1..353
FT                   /note="ATP-dependent kinase YFH7"
FT                   /id="PRO_0000404214"
FT   BINDING         31..39
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   353 AA;  39650 MW;  D4FC34A713C1CF83 CRC64;
     MLDYDALVDQ ALQLLEQNIN KNYRVCIGII GPPGSGKSTV AEKLKEKINS RYHDYLAHEH
     HAEVAVRPLS SAIDLTGDLS VANKELQAEI KAGFYSHVED NNFKPVQVKE SDGSTLIVGR
     GGLDNAVRIK PLRKEANLSP TKPDIAQIVP MDGFHLSRKH LDHFKDPTVA HLRRGSPFTF
     DSNNFLQLCK VLSKTCSLDP NYHSTGPETV NEDNTNSLFD NVTNSFIDLP EISFPGFDHA
     IKDPVADQHT VHKFTRILIL EGLYLLLNQE NWSLIYDAIA STGAFIFWNI VIDEDVIEQR
     VAKRHVKSGI CLSLEEGIQR FRANDQINGR LIQSQSVRNA NKNVKNVYDI RND