ID   YFHC_BACSU              Reviewed;         194 AA.
AC   O31571; Q79EW0;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Putative NAD(P)H nitroreductase YfhC;
DE            EC=1.-.-.-;
GN   Name=yfhC; OrderedLocusNames=BSU08480;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8946165; DOI=10.1093/dnares/3.4.257;
RA   Yamamoto H., Uchiyama S., Sekiguchi J.;
RT   "Cloning and sequencing of a 27.8-kb nucleotide sequence of the 79 degrees-
RT   81 degrees region of the Bacillus subtilis genome containing the sspE
RT   locus.";
RL   DNA Res. 3:257-262(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the nitroreductase family. {ECO:0000305}.
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DR   EMBL; D85082; BAA24469.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12677.1; -; Genomic_DNA.
DR   PIR; D69800; D69800.
DR   RefSeq; NP_388729.1; NC_000964.3.
DR   RefSeq; WP_003243940.1; NZ_JNCM01000032.1.
DR   AlphaFoldDB; O31571; -.
DR   SMR; O31571; -.
DR   STRING; 224308.BSU08480; -.
DR   jPOST; O31571; -.
DR   PaxDb; O31571; -.
DR   PRIDE; O31571; -.
DR   EnsemblBacteria; CAB12677; CAB12677; BSU_08480.
DR   GeneID; 939221; -.
DR   KEGG; bsu:BSU08480; -.
DR   PATRIC; fig|224308.179.peg.915; -.
DR   eggNOG; COG0778; Bacteria.
DR   InParanoid; O31571; -.
DR   OMA; IPEWEQV; -.
DR   PhylomeDB; O31571; -.
DR   BioCyc; BSUB:BSU08480-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd02135; YdjA-like; 1.
DR   Gene3D; 3.40.109.10; -; 1.
DR   InterPro; IPR029479; Nitroreductase.
DR   InterPro; IPR000415; Nitroreductase-like.
DR   InterPro; IPR026021; YdjA-like.
DR   Pfam; PF00881; Nitroreductase; 1.
DR   PIRSF; PIRSF000232; YdjA; 1.
DR   SUPFAM; SSF55469; SSF55469; 1.
PE   3: Inferred from homology;
KW   Flavoprotein; FMN; NAD; NADP; Oxidoreductase; Reference proteome.
FT   CHAIN           1..194
FT                   /note="Putative NAD(P)H nitroreductase YfhC"
FT                   /id="PRO_0000382693"
FT   BINDING         20..22
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT                   /evidence="ECO:0000250"
FT   BINDING         147..148
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT                   /evidence="ECO:0000250"
FT   BINDING         188
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   194 AA;  22455 MW;  C8AE2838CB8DAAFA CRC64;
     MPQTEQIHQH SVLRDIIRSR RSIRKFKQEP VPSAVILDML ETAKYAPNHR VTEPWRFIYV
     SSETGKANLI NTFAAFSKKS KPDMTEEKLQ NFKNTLGRVP GFLLVVFQED ENERARDDDF
     AATSSLIQNL QLLAWEKGIG MVWKSGKILY DKEVHQAFGL QDNERFAAII QTGYPDEAPE
     VKKRTPIRDR FTEM