ID   YFHR_ECOLI              Reviewed;         284 AA.
AC   P77538;
DT   16-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT   24-NOV-2009, sequence version 4.
DT   03-AUG-2022, entry version 145.
DE   RecName: Full=Uncharacterized protein YfhR;
GN   Name=yfhR; OrderedLocusNames=b2534, JW2518;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA   Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA   Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA   Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA   Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT   "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT   genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT   its sequence features.";
RL   DNA Res. 4:91-113(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the serine esterase family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA16428.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; U00096; AAC75587.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAA16428.1; ALT_INIT; Genomic_DNA.
DR   PIR; E65030; E65030.
DR   RefSeq; NP_417029.4; NC_000913.3.
DR   RefSeq; WP_001297705.1; NZ_LN832404.1.
DR   AlphaFoldDB; P77538; -.
DR   SMR; P77538; -.
DR   BioGRID; 4260968; 19.
DR   IntAct; P77538; 5.
DR   STRING; 511145.b2534; -.
DR   ESTHER; ecoli-YfhR; ABHD13-BEM46.
DR   MEROPS; S09.A36; -.
DR   PaxDb; P77538; -.
DR   PRIDE; P77538; -.
DR   EnsemblBacteria; AAC75587; AAC75587; b2534.
DR   EnsemblBacteria; BAA16428; BAA16428; BAA16428.
DR   GeneID; 945059; -.
DR   KEGG; ecj:JW2518; -.
DR   KEGG; eco:b2534; -.
DR   PATRIC; fig|1411691.4.peg.4200; -.
DR   EchoBASE; EB3226; -.
DR   eggNOG; COG1073; Bacteria.
DR   HOGENOM; CLU_029375_2_1_6; -.
DR   InParanoid; P77538; -.
DR   OMA; PNGGHND; -.
DR   PhylomeDB; P77538; -.
DR   BioCyc; EcoCyc:G7328-MON; -.
DR   PRO; PR:P77538; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR022742; Hydrolase_4.
DR   Pfam; PF12146; Hydrolase_4; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..284
FT                   /note="Uncharacterized protein YfhR"
FT                   /id="PRO_0000169252"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   284 AA;  31516 MW;  FB9ED6D7870A3FAA CRC64;
     MALPVNKRVP KILFILFVVA FCVYLVPRVA INFFYYPDDK IYGPDPWSAE SVEFTAKDGT
     RLQGWFIPSS TGPADNAIAT IIHAHGNAGN MSAHWPLVSW LPERNFNVFM FDYRGFGKSK
     GTPSQAGLLD DTQSAINVVR HRSDVNPQRL VLFGQSIGGA NILDVIGRGD REGIRAVILD
     STFASYATIA NQMIPGSGYL LDESYSGENY IASVSPIPLL LIHGKADHVI PWQHSEKLYS
     LAKEPKRLIL IPDGEHIDAF SDRHGDVYRE QMVDFILSAL NPQN