YFI8_YEAST
ID YFI8_YEAST Reviewed; 363 AA.
AC P43599; D6VTP9;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=Uncharacterized protein YFR018C;
GN OrderedLocusNames=YFR018C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7670463; DOI=10.1038/ng0795-261;
RA Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S.,
RA Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H.,
RA Eki T.;
RT "Analysis of the nucleotide sequence of chromosome VI from Saccharomyces
RT cerevisiae.";
RL Nat. Genet. 10:261-268(1995).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- MISCELLANEOUS: Present with 3970 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; D50617; BAA09257.1; -; Genomic_DNA.
DR EMBL; AY692564; AAT92583.1; -; Genomic_DNA.
DR EMBL; BK006940; DAA12459.1; -; Genomic_DNA.
DR PIR; S56273; S56273.
DR RefSeq; NP_116673.1; NM_001179983.1.
DR AlphaFoldDB; P43599; -.
DR SMR; P43599; -.
DR BioGRID; 31171; 48.
DR DIP; DIP-5527N; -.
DR STRING; 4932.YFR018C; -.
DR PaxDb; P43599; -.
DR PRIDE; P43599; -.
DR EnsemblFungi; YFR018C_mRNA; YFR018C; YFR018C.
DR GeneID; 850573; -.
DR KEGG; sce:YFR018C; -.
DR SGD; S000001914; YFR018C.
DR VEuPathDB; FungiDB:YFR018C; -.
DR eggNOG; KOG3946; Eukaryota.
DR GeneTree; ENSGT00390000003107; -.
DR HOGENOM; CLU_045003_1_1_1; -.
DR InParanoid; P43599; -.
DR OMA; CDRVRMP; -.
DR BioCyc; YEAST:G3O-30470-MON; -.
DR Reactome; R-SCE-6798695; Neutrophil degranulation.
DR PRO; PR:P43599; -.
DR Proteomes; UP000002311; Chromosome VI.
DR RNAct; P43599; protein.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:SGD.
DR GO; GO:0016603; F:glutaminyl-peptide cyclotransferase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IBA:GO_Central.
DR GO; GO:0017186; P:peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase; IBA:GO_Central.
DR CDD; cd03880; M28_QC_like; 1.
DR InterPro; IPR037457; M28_QC.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR040234; QC/QCL.
DR PANTHER; PTHR12283; PTHR12283; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
PE 1: Evidence at protein level;
KW Acyltransferase; Reference proteome; Transferase.
FT CHAIN 1..363
FT /note="Uncharacterized protein YFR018C"
FT /id="PRO_0000202688"
SQ SEQUENCE 363 AA; 41031 MW; 70B979735B4923BE CRC64;
MGMKYVLPLR LIGLAYLLVL FQVHRVTGWE LSYEQYHAAH LNEAINPDSG WNKSTKNLLL
PFNRTRVPGS EGSREIQRFI IEHFNNTLAG EWAVETQAFE ENGYRFNNLV MTLQNNASEY
LVLAAHYDTK IAPTGMVGAI DSAASCAALL YTAQFLTHIA CHERTKEYND LESNTVVSNS
TLGVKIVFFD GEEAIEEWGP EDSIYGARRL AAQWLADGTM TRIRLLFLLD LLGSGEEEPL
VPSYYAETHQ EYQLLNRIED DLLFRRGDEI NGESALAAEV ARQRKHLDPT DYRFLGLGHS
VIGDDHTPFL AAGVPVLHAI PLPFPSTWHT VDDDFRHLDA AETRHWALLV CEFVVQSLRS
RNQ