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YFIE_ECOLI
ID   YFIE_ECOLI              Reviewed;         293 AA.
AC   P33634; P76592; P76998;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YfiE;
GN   Name=yfiE; OrderedLocusNames=b2577, JW2561;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RA   Nashimoto H.;
RT   "Non-ribosomal proteins affecting the assembly of ribosomes in Escherichia
RT   coli.";
RL   (In) Nierhaus K.H. (eds.);
RL   The translational apparatus, pp.185-195, Plenum Press, New York (1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RA   Nashimoto H., Saito N.;
RL   Submitted (SEP-1995) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-208.
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA   Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA   Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA   Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA   Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT   "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT   genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT   its sequence features.";
RL   DNA Res. 4:91-113(1997).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; D13169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; D64044; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; U00096; AAC75630.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAA20920.2; -; Genomic_DNA.
DR   PIR; H65035; H65035.
DR   RefSeq; NP_417072.4; NC_000913.3.
DR   RefSeq; WP_001300638.1; NZ_LN832404.1.
DR   AlphaFoldDB; P33634; -.
DR   SMR; P33634; -.
DR   BioGRID; 4261636; 18.
DR   IntAct; P33634; 3.
DR   STRING; 511145.b2577; -.
DR   PaxDb; P33634; -.
DR   PRIDE; P33634; -.
DR   EnsemblBacteria; AAC75630; AAC75630; b2577.
DR   EnsemblBacteria; BAA20920; BAA20920; BAA20920.
DR   GeneID; 947064; -.
DR   KEGG; ecj:JW2561; -.
DR   KEGG; eco:b2577; -.
DR   PATRIC; fig|1411691.4.peg.4157; -.
DR   EchoBASE; EB1733; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_1_6; -.
DR   InParanoid; P33634; -.
DR   OMA; ACEEYFK; -.
DR   PhylomeDB; P33634; -.
DR   BioCyc; EcoCyc:EG11785-MON; -.
DR   PRO; PR:P33634; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..293
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YfiE"
FT                   /id="PRO_0000105793"
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   CONFLICT        209..293
FT                   /note="RITVENTIELISIESIKRCVAANIGVSYLPRFAVAKELECGELIELPFGEQS
FT                   QTITAMCAHHAGKAVSPAMHTFIQCVEESFVAG -> DHGGKHH (in Ref. 1;
FT                   D13169 and 2; D64044)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   293 AA;  33243 MW;  1C54C96647799632 CRC64;
     MDLRRFITLK TVVEEGSFLR ASQKLCCTQS TVTFHIQQLE QEFSVQLFEK IGRRMCLTRE
     GKKLLPHIYE LTRVMDTLRE AAKKESDPDG ELRVVSGETL LSYRMPQVLQ RFRQRAPKVR
     LSLQSLNCYV IRDALLNDEA DVGVFYRVGN DDALNRRELG EQSLVLVASP QIADVDFTEP
     GRHNACSFII NEPQCVFRQI FESTLRQRRI TVENTIELIS IESIKRCVAA NIGVSYLPRF
     AVAKELECGE LIELPFGEQS QTITAMCAHH AGKAVSPAMH TFIQCVEESF VAG
 
 
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