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YFIR_ECOLI
ID   YFIR_ECOLI              Reviewed;         172 AA.
AC   P64548; P76597; Q2MAF0;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Protein YfiR {ECO:0000305};
DE   Flags: Precursor;
GN   Name=yfiR; OrderedLocusNames=b2603, JW2584;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [3]
RP   FUNCTION, AND ACTIVITY REGULATION.
RX   PubMed=27507823; DOI=10.1128/mbio.00822-16;
RA   Kim H.K., Harshey R.M.;
RT   "A diguanylate cyclase acts as a cell division inhibitor in a two-step
RT   response to reductive and envelope stresses.";
RL   MBio 7:E00822-E00822(2016).
CC   -!- FUNCTION: Repressor of the cell division arrest function of DgcN.
CC       Prevents DgcN relocation to the midcell. {ECO:0000269|PubMed:27507823}.
CC   -!- ACTIVITY REGULATION: Inactivated by reductive stress.
CC       {ECO:0000269|PubMed:27507823}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
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DR   EMBL; U00096; AAC75652.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76756.1; -; Genomic_DNA.
DR   PIR; F65038; F65038.
DR   RefSeq; NP_417094.1; NC_000913.3.
DR   RefSeq; WP_001212391.1; NZ_STEB01000040.1.
DR   AlphaFoldDB; P64548; -.
DR   SMR; P64548; -.
DR   BioGRID; 4260612; 8.
DR   IntAct; P64548; 2.
DR   STRING; 511145.b2603; -.
DR   PaxDb; P64548; -.
DR   PRIDE; P64548; -.
DR   EnsemblBacteria; AAC75652; AAC75652; b2603.
DR   EnsemblBacteria; BAE76756; BAE76756; BAE76756.
DR   GeneID; 66673508; -.
DR   GeneID; 947090; -.
DR   KEGG; ecj:JW2584; -.
DR   KEGG; eco:b2603; -.
DR   PATRIC; fig|1411691.4.peg.4136; -.
DR   EchoBASE; EB3977; -.
DR   eggNOG; ENOG5032MZ8; Bacteria.
DR   HOGENOM; CLU_102469_1_0_6; -.
DR   InParanoid; P64548; -.
DR   OMA; LSYARWP; -.
DR   PhylomeDB; P64548; -.
DR   BioCyc; EcoCyc:G7354-MON; -.
DR   PRO; PR:P64548; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0071978; P:bacterial-type flagellum-dependent swarming motility; IMP:EcoCyc.
DR   InterPro; IPR025293; YfiR/HmsC-like.
DR   Pfam; PF13689; DUF4154; 1.
PE   3: Inferred from homology;
KW   Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..172
FT                   /note="Protein YfiR"
FT                   /id="PRO_0000013892"
SQ   SEQUENCE   172 AA;  18978 MW;  2E2CC812E49F3AD5 CRC64;
     MRFSHRLFLL LILLLTGAPI LAQEPSDVAK NVRMMVSGIV SYTRWPALSG PPKLCIFSSS
     RFSTALQENA ATSLPYLPVI IHTQQEAMIS GCNGFYFGNE SPTFQMELTE QYPSKALLLI
     AEQNTECIIG SAFCLIIHNN DVRFAVNLDA LSRSGVKVNP DVLMLARKKN DG
 
 
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