YFJD_ECOLI
ID YFJD_ECOLI Reviewed; 428 AA.
AC P37908; P76600; P76601; P77009; Q6BF70;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 10-JUL-2007, sequence version 5.
DT 03-AUG-2022, entry version 165.
DE RecName: Full=UPF0053 inner membrane protein YfjD;
GN Name=yfjD; Synonyms=ypjE; OrderedLocusNames=b4461, JW5415;
GN ORFNames=b2612/b2613;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT its sequence features.";
RL DNA Res. 4:91-113(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP SEQUENCE REVISION.
RX PubMed=16397293; DOI=10.1093/nar/gkj405;
RA Riley M., Abe T., Arnaud M.B., Berlyn M.K.B., Blattner F.R.,
RA Chaudhuri R.R., Glasner J.D., Horiuchi T., Keseler I.M., Kosuge T.,
RA Mori H., Perna N.T., Plunkett G. III, Rudd K.E., Serres M.H., Thomas G.H.,
RA Thomson N.R., Wishart D., Wanner B.L.;
RT "Escherichia coli K-12: a cooperatively developed annotation snapshot
RT -- 2005.";
RL Nucleic Acids Res. 34:1-9(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 322-428.
RC STRAIN=B178;
RX PubMed=3045760; DOI=10.1093/nar/16.15.7545;
RA Lipinska B., King J., Ang D., Georgopoulos C.;
RT "Sequence analysis and transcriptional regulation of the Escherichia coli
RT grpE gene, encoding a heat shock protein.";
RL Nucleic Acids Res. 16:7545-7562(1988).
RN [6]
RP IDENTIFICATION.
RA Rudd K.E.;
RL Unpublished observations (AUG-1994).
RN [7]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the UPF0053 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA16497.2; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=X07863; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; U00096; AAT48144.3; -; Genomic_DNA.
DR EMBL; AP009048; BAA16497.2; ALT_INIT; Genomic_DNA.
DR EMBL; X07863; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; WP_010723175.1; NZ_STEB01000040.1.
DR RefSeq; YP_026171.3; NC_000913.3.
DR AlphaFoldDB; P37908; -.
DR SMR; P37908; -.
DR BioGRID; 4260620; 11.
DR BioGRID; 853486; 1.
DR DIP; DIP-12070N; -.
DR IntAct; P37908; 2.
DR STRING; 511145.b4461; -.
DR TCDB; 1.A.112.2.5; the cyclin m mg2+ exporter (cnnm) family.
DR jPOST; P37908; -.
DR PaxDb; P37908; -.
DR PRIDE; P37908; -.
DR EnsemblBacteria; AAT48144; AAT48144; b4461.
DR EnsemblBacteria; BAA16497; BAA16497; BAA16497.
DR GeneID; 2847739; -.
DR GeneID; 67414070; -.
DR KEGG; ecj:JW5415; -.
DR KEGG; eco:b4461; -.
DR PATRIC; fig|511145.12.peg.2710; -.
DR EchoBASE; EB2336; -.
DR eggNOG; COG4536; Bacteria.
DR HOGENOM; CLU_015237_4_1_6; -.
DR InParanoid; P37908; -.
DR OMA; TIGRQHP; -.
DR PhylomeDB; P37908; -.
DR BioCyc; EcoCyc:G7356-MON; -.
DR PRO; PR:P37908; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; -; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR Pfam; PF01595; DUF21; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; SSF54631; 1.
DR SUPFAM; SSF56176; SSF56176; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 1: Evidence at protein level;
KW CBS domain; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Repeat; Transmembrane; Transmembrane helix.
FT CHAIN 1..428
FT /note="UPF0053 inner membrane protein YfjD"
FT /id="PRO_0000088357"
FT TOPO_DOM 1..3
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 4..24
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 25..64
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 86..91
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 113..129
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 151..428
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 2..192
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01193"
FT DOMAIN 208..270
FT /note="CBS 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 272..332
FT /note="CBS 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
SQ SEQUENCE 428 AA; 48044 MW; 38456865EDBCB151 CRC64;
MEHISTTTLI IILIIMVVIS AYFSGSETGM MTLNRYRLRH MAKQGNRSAK RVEKLLRKPD
RLISLVLIGN NLVNILASAL GTIVGMRLYG DAGVAIATGV LTFVVLVFAE VLPKTIAALY
PEKVAYPSSF LLAPLQILMM PLVWLLNAIT RMLMRMMGIK TDIVVSGSLS KEELRTIVHE
SRSQISRRNQ DMLLSVLDLE KMTVDDIMVP RSEIIGIDIN DDWKSILRQL SHSPHGRIVL
YRDSLDDAIS MLRVREAWRL MSEKKEFTKE TMLRAADEIY FVPEGTPLST QLVKFQRNKK
KVGLVVNEYG DIQGLVTVED ILEEIVGDFT TSMSPTLAEE VTPQNDGSVI IDGTANVREI
NKAFNWHLPE DDARTVNGVI LEALEEIPVA GTRVRIGEYD IDILDVQDNM IKQVKVFPVK
PLRESVAE
