YFJR_BACSU
ID YFJR_BACSU Reviewed; 286 AA.
AC O34969;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 24-MAR-2009, sequence version 2.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Uncharacterized oxidoreductase YfjR;
DE EC=1.1.-.-;
GN Name=yfjR; OrderedLocusNames=BSU07990;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / AC327;
RX PubMed=8969503; DOI=10.1099/13500872-142-11-3057;
RA Yamamoto H., Uchiyama S., Sekiguchi J.;
RT "Cloning and sequencing of a 40.6 kb segment in the 73 degrees-76 degrees
RT region of the Bacillus subtilis chromosome containing genes for trehalose
RT metabolism and acetoin utilization.";
RL Microbiology 142:3057-3065(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
CC -!- SIMILARITY: Belongs to the HIBADH-related family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA23388.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=BAA24303.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; D83967; BAA23388.1; ALT_INIT; Genomic_DNA.
DR EMBL; D78509; BAA24303.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL009126; CAB12628.2; -; Genomic_DNA.
DR PIR; A69807; A69807.
DR RefSeq; NP_388680.2; NC_000964.3.
DR RefSeq; WP_003243106.1; NZ_JNCM01000032.1.
DR AlphaFoldDB; O34969; -.
DR SMR; O34969; -.
DR STRING; 224308.BSU07990; -.
DR PaxDb; O34969; -.
DR PRIDE; O34969; -.
DR EnsemblBacteria; CAB12628; CAB12628; BSU_07990.
DR GeneID; 939198; -.
DR KEGG; bsu:BSU07990; -.
DR PATRIC; fig|224308.179.peg.864; -.
DR eggNOG; COG2084; Bacteria.
DR InParanoid; O34969; -.
DR OMA; CKGVMGR; -.
DR PhylomeDB; O34969; -.
DR BioCyc; BSUB:BSU07990-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IBA:GO_Central.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 1.10.1040.10; -; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR029154; NADP-bd.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; SSF48179; 1.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 3: Inferred from homology;
KW NAD; Oxidoreductase; Reference proteome.
FT CHAIN 1..286
FT /note="Uncharacterized oxidoreductase YfjR"
FT /id="PRO_0000173067"
FT ACT_SITE 171
FT /evidence="ECO:0000250"
FT BINDING 4..18
FT /ligand="NAD(+)"
FT /ligand_id="ChEBI:CHEBI:57540"
FT /evidence="ECO:0000250"
FT BINDING 95
FT /ligand="NAD(+)"
FT /ligand_id="ChEBI:CHEBI:57540"
FT /evidence="ECO:0000250"
FT BINDING 239
FT /ligand="NAD(+)"
FT /ligand_id="ChEBI:CHEBI:57540"
FT /evidence="ECO:0000250"
SQ SEQUENCE 286 AA; 30474 MW; DDFAF89B288E3AA1 CRC64;
MKIAVIGLGN MGQPIARNVL QAGYELTVYN RTKQKTEDLV TEGAQAADTP RLAAKSADIV
ITMLADDDSV STVTFGEDGL LEGLAENGIH ISMSTISVEF SEKLAAAHAE KGQFFLAAPV
LGRPDAAAKA ALRIITAGPA EAKQAAKPLL DSLSQQIFDV GEESKTANAA KISINFLLVS
MLEALSESFL MMEKYGLEQK QFLEIASALF GSPVYQNYGT IMAEQKFEPA GFKMSLGLKD
TNLALAAAKR VSANLPLAEL AKSHFESGIE KGFGDLDWAA LIKCIK
