YFKR_BACSU
ID YFKR_BACSU Reviewed; 384 AA.
AC O35028; Q79EU3;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Putative spore germination protein YfkR;
DE Flags: Precursor;
GN Name=yfkR; OrderedLocusNames=BSU07780;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / AC327;
RX PubMed=9272861; DOI=10.1016/s0378-1119(97)00130-3;
RA Yamamoto H., Uchiyama S., Nugroho F.A., Sekiguchi J.;
RT "Cloning and sequencing of a 35.7 kb in the 70 degree-73 degree region of
RT the Bacillus subtilis genome reveal genes for a new two-component system,
RT three spore germination proteins, an iron uptake system and a general
RT stress response protein.";
RL Gene 194:191-199(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP FUNCTION.
RX PubMed=10762253; DOI=10.1128/jb.182.9.2513-2519.2000;
RA Paidhungat M., Setlow P.;
RT "Role of ger proteins in nutrient and nonnutrient triggering of spore
RT germination in Bacillus subtilis.";
RL J. Bacteriol. 182:2513-2519(2000).
CC -!- FUNCTION: May be involved in spore germination.
CC {ECO:0000269|PubMed:10762253}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC -!- SIMILARITY: Belongs to the GerABKC lipoprotein family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; D86417; BAA22291.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB12607.1; -; Genomic_DNA.
DR PIR; D69809; D69809.
DR RefSeq; NP_388659.1; NC_000964.3.
DR RefSeq; WP_003243672.1; NZ_JNCM01000032.1.
DR AlphaFoldDB; O35028; -.
DR SMR; O35028; -.
DR STRING; 224308.BSU07780; -.
DR PaxDb; O35028; -.
DR PRIDE; O35028; -.
DR EnsemblBacteria; CAB12607; CAB12607; BSU_07780.
DR GeneID; 936126; -.
DR KEGG; bsu:BSU07780; -.
DR PATRIC; fig|224308.179.peg.842; -.
DR eggNOG; ENOG502Z9N7; Bacteria.
DR OMA; ARVPQNR; -.
DR PhylomeDB; O35028; -.
DR BioCyc; BSUB:BSU07780-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009847; P:spore germination; IEA:InterPro.
DR Gene3D; 3.30.300.210; -; 1.
DR InterPro; IPR008844; Spore_GerAC.
DR InterPro; IPR038501; Spore_GerAC_C_sf.
DR PANTHER; PTHR35789; PTHR35789; 1.
DR Pfam; PF05504; Spore_GerAC; 1.
DR TIGRFAMs; TIGR02887; spore_ger_x_C; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane; Germination; Lipoprotein; Membrane; Palmitate;
KW Reference proteome; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 21..384
FT /note="Putative spore germination protein YfkR"
FT /id="PRO_0000360417"
FT LIPID 21
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT LIPID 21
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ SEQUENCE 384 AA; 42796 MW; AA2E00B76C356619 CRC64;
MKKTIYKCVL PLLICILLTG CWDRTEINDI AFVVSSAIDK KKDQYRVAMQ IPLVGQLGGQ
TGGGGGTAGS KTWYVDSASG TTIREANNKL QTSLSRTINT SHRRTVIIGE DMARDGVAPV
FDILTRNPQN RLTALILVSR GEARDILNTD VQLEQFPAEM IRELAIIATS RPVFLSRFMS
DLVEIGSDPY APVISASKTK PGGKGKSNLK IDGLAIFKKD RLMDIFKDEH MTAALMLLNQ
ARQPEFIVDL PNQMGQASIQ LQKSNASFHA AEKNGKLSMT IEIRAKGIIM ENQSTYETRE
NDQYYIIQKA LNRTIKKDVI STVHRLQKLK ADPAGFQDRT IRSTATTKNL LKKEWEEVYK
DMEVHVVPIV TIEQGGVLYK TISH
