YFM6_YEAST
ID YFM6_YEAST Reviewed; 122 AA.
AC P43624;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Putative uncharacterized protein YFR056C;
GN OrderedLocusNames=YFR056C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204511 / S288c / AB972;
RX PubMed=8686379;
RX DOI=10.1002/(sici)1097-0061(199602)12:2<149::aid-yea893>3.0.co;2-g;
RA Eki T., Naitou M., Hagiwara H., Ozawa M., Sasanuma S., Sasanuma M.,
RA Tsuchiya Y., Shibata T., Hanaoka F., Murakami Y.;
RT "Analysis of a 36.2 kb DNA sequence including the right telomere of
RT chromosome VI from Saccharomyces cerevisiae.";
RL Yeast 12:149-167(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7670463; DOI=10.1038/ng0795-261;
RA Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S.,
RA Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H.,
RA Eki T.;
RT "Analysis of the nucleotide sequence of chromosome VI from Saccharomyces
RT cerevisiae.";
RL Nat. Genet. 10:261-268(1995).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP INDUCTION.
RX PubMed=12379856; DOI=10.1038/ng1017;
RA Suka N., Luo K., Grunstein M.;
RT "Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine
RT 16 and spreading of heterochromatin.";
RL Nat. Genet. 32:378-383(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- INDUCTION: Silenced by SIR3. {ECO:0000269|PubMed:12379856}.
CC -!- MISCELLANEOUS: Partially overlaps YFR055W. {ECO:0000305}.
CC -!- CAUTION: Product of a dubious gene prediction unlikely to encode a
CC functional protein. Because of that it is not part of the S.cerevisiae
CC S288c complete/reference proteome set. {ECO:0000305|PubMed:24374639}.
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DR EMBL; D50617; BAA09294.1; -; Genomic_DNA.
DR EMBL; AY693240; AAT93259.1; -; Genomic_DNA.
DR PIR; S56310; S56310.
DR AlphaFoldDB; P43624; -.
DR IntAct; P43624; 1.
DR STRING; 4932.YFR056C; -.
DR PaxDb; P43624; -.
DR PRIDE; P43624; -.
DR EnsemblFungi; YFR056C_mRNA; YFR056C; YFR056C.
DR SGD; S000001951; YFR056C.
DR HOGENOM; CLU_2028521_0_0_1; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 5: Uncertain;
KW Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..122
FT /note="Putative uncharacterized protein YFR056C"
FT /id="PRO_0000202700"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 122 AA; 14003 MW; 41603FC52FE3B949 CRC64;
MMVDPLYKGG LTKPLCSSGL RPITDSCVVI PNFDNSVRSI IVVNILVFAG ILYSQFRNTL
SIFSLWCPNT RAVFLFICPC LLYFYQGIFS TDEQIGTFNI IWMLRRLTIE LIIRNLNAEK
ER