YFNB_BACSU
ID YFNB_BACSU Reviewed; 235 AA.
AC O06480; Q797A8;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1997, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Putative HAD-hydrolase YfnB;
DE EC=3.-.-.-;
GN Name=yfnB; OrderedLocusNames=BSU07330;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / AC327;
RX PubMed=9141694; DOI=10.1099/00221287-143-4-1317;
RA Yamamoto H., Uchiyama S., Nugroho F.A., Sekiguchi J.;
RT "A 23.4 kb segment at the 69 degrees-70 degrees region of the Bacillus
RT subtilis genome.";
RL Microbiology 143:1317-1320(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP X-RAY CRYSTALLOGRAPHY (1.72 ANGSTROMS).
RG Midwest center for structural genomics (MCSG);
RT "The crystal structure of yfnB from Bacillus subtilis subsp. subtilis str.
RT 168.";
RL Submitted (SEP-2008) to the PDB data bank.
CC -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily. YjjG family.
CC {ECO:0000305}.
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DR EMBL; D86418; BAA20111.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB12552.1; -; Genomic_DNA.
DR PIR; E69814; E69814.
DR RefSeq; NP_388614.1; NC_000964.3.
DR RefSeq; WP_003244307.1; NZ_JNCM01000032.1.
DR PDB; 3ED5; X-ray; 1.72 A; A=1-235.
DR PDB; 3I76; X-ray; 2.00 A; A/B/C=2-234.
DR PDBsum; 3ED5; -.
DR PDBsum; 3I76; -.
DR AlphaFoldDB; O06480; -.
DR SMR; O06480; -.
DR STRING; 224308.BSU07330; -.
DR PaxDb; O06480; -.
DR PRIDE; O06480; -.
DR DNASU; 936095; -.
DR EnsemblBacteria; CAB12552; CAB12552; BSU_07330.
DR GeneID; 936095; -.
DR KEGG; bsu:BSU07330; -.
DR PATRIC; fig|224308.179.peg.795; -.
DR eggNOG; COG1011; Bacteria.
DR InParanoid; O06480; -.
DR OMA; DHTLWDF; -.
DR PhylomeDB; O06480; -.
DR BioCyc; BSUB:BSU07330-MON; -.
DR SABIO-RK; O06480; -.
DR EvolutionaryTrace; O06480; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0008253; F:5'-nucleotidase activity; IEA:InterPro.
DR Gene3D; 1.10.150.240; -; 1.
DR Gene3D; 3.40.50.1000; -; 1.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR006439; HAD-SF_hydro_IA.
DR InterPro; IPR011951; HAD-SF_hydro_IA_YjjG/PynA.
DR InterPro; IPR041492; HAD_2.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR023198; PGP-like_dom2.
DR Pfam; PF13419; HAD_2; 1.
DR SUPFAM; SSF56784; SSF56784; 1.
DR TIGRFAMs; TIGR01549; HAD-SF-IA-v1; 1.
DR TIGRFAMs; TIGR02254; YjjG/YfnB; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Hydrolase; Reference proteome.
FT CHAIN 1..235
FT /note="Putative HAD-hydrolase YfnB"
FT /id="PRO_0000360840"
FT ACT_SITE 10
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT STRAND 6..9
FT /evidence="ECO:0007829|PDB:3ED5"
FT TURN 13..15
FT /evidence="ECO:0007829|PDB:3ED5"
FT HELIX 18..32
FT /evidence="ECO:0007829|PDB:3ED5"
FT HELIX 39..57
FT /evidence="ECO:0007829|PDB:3ED5"
FT HELIX 63..77
FT /evidence="ECO:0007829|PDB:3ED5"
FT HELIX 84..95
FT /evidence="ECO:0007829|PDB:3ED5"
FT HELIX 105..113
FT /evidence="ECO:0007829|PDB:3ED5"
FT STRAND 116..122
FT /evidence="ECO:0007829|PDB:3ED5"
FT HELIX 126..135
FT /evidence="ECO:0007829|PDB:3ED5"
FT HELIX 139..141
FT /evidence="ECO:0007829|PDB:3ED5"
FT STRAND 143..147
FT /evidence="ECO:0007829|PDB:3ED5"
FT HELIX 148..150
FT /evidence="ECO:0007829|PDB:3ED5"
FT HELIX 158..166
FT /evidence="ECO:0007829|PDB:3ED5"
FT HELIX 173..175
FT /evidence="ECO:0007829|PDB:3ED5"
FT STRAND 176..181
FT /evidence="ECO:0007829|PDB:3ED5"
FT TURN 183..186
FT /evidence="ECO:0007829|PDB:3ED5"
FT HELIX 187..192
FT /evidence="ECO:0007829|PDB:3ED5"
FT STRAND 196..200
FT /evidence="ECO:0007829|PDB:3ED5"
FT STRAND 214..219
FT /evidence="ECO:0007829|PDB:3ED5"
FT HELIX 220..222
FT /evidence="ECO:0007829|PDB:3ED5"
FT HELIX 223..227
FT /evidence="ECO:0007829|PDB:3ED5"
SQ SEQUENCE 235 AA; 27381 MW; 880310113AC4CF1B CRC64;
MKRYRTLLFD VDDTILDFQA AEALALRLLF EDQNIPLTND MKAQYKTINQ GLWRAFEEGK
MTRDEVVNTR FSALLKEYGY EADGALLEQK YRRFLEEGHQ LIDGAFDLIS NLQQQFDLYI
VTNGVSHTQY KRLRDSGLFP FFKDIFVSED TGFQKPMKEY FNYVFERIPQ FSAEHTLIIG
DSLTADIKGG QLAGLDTCWM NPDMKPNVPE IIPTYEIRKL EELYHILNIE NTVSC
