ID   YFNG_BACSU              Reviewed;         322 AA.
AC   O06485; Q797B1;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-JAN-2009, sequence version 2.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Putative sugar dehydratase/epimerase YfnG;
GN   Name=yfnG; OrderedLocusNames=BSU07280;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / AC327;
RX   PubMed=9141694; DOI=10.1099/00221287-143-4-1317;
RA   Yamamoto H., Uchiyama S., Nugroho F.A., Sekiguchi J.;
RT   "A 23.4 kb segment at the 69 degrees-70 degrees region of the Bacillus
RT   subtilis genome.";
RL   Microbiology 143:1317-1320(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- COFACTOR:
CC       Name=NAD(+); Xref=ChEBI:CHEBI:57540; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA20116.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; D86418; BAA20116.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AL009126; CAB12547.2; -; Genomic_DNA.
DR   PIR; B69815; B69815.
DR   RefSeq; NP_388609.1; NC_000964.3.
DR   RefSeq; WP_003244102.1; NZ_JNCM01000032.1.
DR   AlphaFoldDB; O06485; -.
DR   SMR; O06485; -.
DR   STRING; 224308.BSU07280; -.
DR   PaxDb; O06485; -.
DR   PRIDE; O06485; -.
DR   DNASU; 938783; -.
DR   EnsemblBacteria; CAB12547; CAB12547; BSU_07280.
DR   GeneID; 938783; -.
DR   KEGG; bsu:BSU07280; -.
DR   PATRIC; fig|224308.179.peg.790; -.
DR   eggNOG; COG0451; Bacteria.
DR   InParanoid; O06485; -.
DR   OMA; CYENREW; -.
DR   BioCyc; BSUB:BSU07280-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF16363; GDP_Man_Dehyd; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; NAD; Reference proteome.
FT   CHAIN           1..322
FT                   /note="Putative sugar dehydratase/epimerase YfnG"
FT                   /id="PRO_0000359980"
FT   ACT_SITE        152
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   BINDING         8..36
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
FT   BINDING         128
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   322 AA;  36427 MW;  80E68CBC6765C0BF CRC64;
     MSFWKNKNVF VTGCTGLLGS YLVKELIEQG ANVTGLVRDH VPQSNLYQGE HIKKMNIVRG
     SLEDLAVIER ALGEYEIDTV FHLAAQAIVG VANRNPISTF EANILGTWNI LEACRKHPLI
     KRVIVASSDK AYGDQENLPY DENMPLQGKH PYDVSKSCAD LISHTYFHTY GLPVCITRCG
     NLYGGGDLNF NRIIPQTIQL VLNGEAPEIR SDGTFVRDYF YIEDAVQAYL LLAEKMEENN
     LAGEAFNFSN EIQLTVLELV EKILKKMNSN LKPKVLNQGS NEIKHQYLSA EKARKLLNWT
     PAYTIDEGLE KTIEWYTEFF KK