ID   YFP3_SCHPO              Reviewed;         886 AA.
AC   O14260;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=UPF0592 membrane protein C7D4.03c;
GN   ORFNames=SPAC7D4.03c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0592 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAB16720.1; -; Genomic_DNA.
DR   PIR; T39081; T39081.
DR   RefSeq; NP_593856.1; NM_001019285.2.
DR   AlphaFoldDB; O14260; -.
DR   BioGRID; 278566; 1.
DR   MaxQB; O14260; -.
DR   PaxDb; O14260; -.
DR   EnsemblFungi; SPAC7D4.03c.1; SPAC7D4.03c.1:pep; SPAC7D4.03c.
DR   GeneID; 2542089; -.
DR   KEGG; spo:SPAC7D4.03c; -.
DR   PomBase; SPAC7D4.03c; -.
DR   VEuPathDB; FungiDB:SPAC7D4.03c; -.
DR   eggNOG; ENOG502QWKM; Eukaryota.
DR   HOGENOM; CLU_003877_1_0_1; -.
DR   InParanoid; O14260; -.
DR   OMA; FCAKILV; -.
DR   PhylomeDB; O14260; -.
DR   PRO; PR:O14260; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005078; F:MAP-kinase scaffold activity; ISO:PomBase.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; ISO:PomBase.
DR   InterPro; IPR013887; UPF0592.
DR   Pfam; PF08578; DUF1765; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..886
FT                   /note="UPF0592 membrane protein C7D4.03c"
FT                   /id="PRO_0000339166"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        374..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        400..420
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          87..112
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   886 AA;  101026 MW;  64462DD96392ECC6 CRC64;
     MGDFQSRYEI LAAIMGPPNT ASFKEEEHSG SQTKNYPVVV KCIQEHDPVD TTNVLVADDL
     DSNFEPFSIT DDYGKYENTL VSHSSTILNE PYNESPSSSS SDSSSRSTSP FSQLSSQSLR
     LNAEEIAPSS LINKAVQSTL RLSEPLVSPI KCPLSEQFIN FINQQDSDKV VLIRGFLLPH
     LASLTTKNVS EPELDKLRHS LYNWWVSILR RLQSNISTSE RITYTKAILA IAKHHCWNKV
     EHSALLYLEH QLILYDTLTF VVHLLSQKSL PYSLTTFCAS ILVLSFFQLP LFADHFLSAL
     DVKKKYIDAL GSSFDEKIMI ISHKYLAPFF TDQFSSTMHP YYPKRTSTPF TIGYNRQPIE
     FTRAWMRRFK SSTGGFFFEF LSCYHSFLAL QFSFELPDNV IYFAPGYICL HAYLLELTIS
     VIHISDKKPL MLPTGHEQFP CKTLPEVNPS MEEYNPKMPV TATTLSTLQQ FVGHIKDAFK
     KIGDCRQEQM RLLAVLEQVL INVAKNTPAF NLQSCFLLCS LVEQCFGVFN DFSHRFDFSF
     WISVAKRLIS TSHNMSIVRS ITFIYAVWPY LDIKSKELVT LQWLLEENTF QELFLHWSPL
     VRAYFQRLVC WRFLKLDDME EFQFKGTVTL RVKNLLKHYF TAQALYHEEC LVNGRASPIT
     KPSEPVPMRR LTIVCNHYQN YGNSESTEFE LSNYKQDDGT IQALVTDVVS ISNSFSSGLK
     KAFGSLFKNV SGLPAETEIA YHHTLSASNS YVFTDLVDNP DSMLKSTLKY RFVFKFSPSQ
     PLSSLGKNKE KYDALLERSS HGVLPVQSKM LLYNSNHISC PLSSIKGVSV NGKRLVYTSR
     ALVEWALVVN EFDHALSLRK GNETEDMEAP TLTVRIPKSY ASNIYN