YFPC_SCHPO
ID YFPC_SCHPO Reviewed; 759 AA.
AC O14267;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Uncharacterized protein C7D4.12c;
GN ORFNames=SPAC7D4.12c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the ThrE exporter (TC 2.A.79) family.
CC {ECO:0000305}.
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DR EMBL; CU329670; CAB16729.1; -; Genomic_DNA.
DR PIR; T39090; T39090.
DR RefSeq; NP_593846.1; NM_001019275.2.
DR AlphaFoldDB; O14267; -.
DR BioGRID; 278255; 22.
DR STRING; 4896.SPAC7D4.12c.1; -.
DR iPTMnet; O14267; -.
DR MaxQB; O14267; -.
DR PaxDb; O14267; -.
DR PRIDE; O14267; -.
DR EnsemblFungi; SPAC7D4.12c.1; SPAC7D4.12c.1:pep; SPAC7D4.12c.
DR GeneID; 2541761; -.
DR KEGG; spo:SPAC7D4.12c; -.
DR PomBase; SPAC7D4.12c; -.
DR VEuPathDB; FungiDB:SPAC7D4.12c; -.
DR eggNOG; ENOG502QPMM; Eukaryota.
DR HOGENOM; CLU_007078_2_1_1; -.
DR InParanoid; O14267; -.
DR OMA; FAHGCAS; -.
DR PhylomeDB; O14267; -.
DR PRO; PR:O14267; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; ISM:PomBase.
DR GO; GO:0015171; F:amino acid transmembrane transporter activity; ISM:PomBase.
DR InterPro; IPR010619; ThrE.
DR InterPro; IPR024528; ThrE_2.
DR Pfam; PF06738; ThrE; 1.
DR Pfam; PF12821; ThrE_2; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..759
FT /note="Uncharacterized protein C7D4.12c"
FT /id="PRO_0000372379"
FT TRANSMEM 434..454
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 456..476
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 486..505
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 517..537
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 555..575
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 597..617
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 620..640
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 643..663
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 670..690
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 726..746
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 188..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 759 AA; 83359 MW; 68D8EA7B5D96924D CRC64;
MDGNRRVRFN TDRRPYLSPL QTSFPSSTSF QTPTFLIEED DEDTEDDDGP QVLPVHRAPS
PAAFRKRGSI TSMDQYLVNM PAVPSPTASK VGLLDARNTD VESYAASYKT QSSSNSVNSL
PMRRPTLDRS YSAPMIAAKN LQSDPEKMSN VESTNELPST TTEAYKLVAA HTAARLEHMR
LNALKAANDE GEDVKDNEQD DNIDESDPFA NPKASYRGGV LSNLLKLYTN SNTVTSSRIS
LKHTDPTKWQ KHAKRTASSN SLTDLLHASN QTFMAPASGL QSTEEIPQFS KTGHSRGRKF
NFHHHSRKNS GLNEEYKITI HLADILQRQK YILKLCRALM VYGAPSHRLE EHMASAAKVL
EIEGQFLYIP GCMIVSFGDV NTHTSDMHIV RVNQTIDLGR LKLVHDIYKA VLHDRMGVEE
AIRGLDEIFK SPPYFRTWIL VVFYGFASAT ILPMSFQGGW IDLPIAFILG CLVGILQHYI
APRSTMYNSL FEVTGSIITS FLSRAFGSIR YSGGRRFCFS ALAEGAIVLI LPGYIVLCGS
LELQSKNIVA GGVRMFYAII YSLFLSFGIS IGAALYGWMD HNATDSTSCP VSTQMDDKWK
ILFVPLFTLC LLIVNQARPS QWPVSIFISC AGYVVNYFTA KHFGSNPIAN AIGSFAIGCL
GNIYSRLGRG VAFAAVLPAI FVQVPSGLAA QGGISSGIEV ATSLTNNTYN TSSSSTLDVN
SLKFGLVMVQ IAIGISVGLF ASALVVYPFG KRRSGLFSF
