ID   YFT6_SCHPO              Reviewed;         621 AA.
AC   Q9UUG2;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Uncharacterized leucine-rich repeat-containing protein C926.06c;
GN   ORFNames=SPAC926.06c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1] {ECO:0000312|EMBL:CAB54154.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2] {ECO:0000305}
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
RN   [3]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-269; SER-271; SER-274;
RP   SER-290 AND SER-292, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}. Vacuole membrane
CC       {ECO:0000269|PubMed:16823372}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU329670; CAB54154.1; -; Genomic_DNA.
DR   PIR; T39204; T39204.
DR   RefSeq; NP_594367.1; NM_001019788.2.
DR   AlphaFoldDB; Q9UUG2; -.
DR   SMR; Q9UUG2; -.
DR   BioGRID; 279949; 18.
DR   STRING; 4896.SPAC926.06c.1; -.
DR   iPTMnet; Q9UUG2; -.
DR   MaxQB; Q9UUG2; -.
DR   PaxDb; Q9UUG2; -.
DR   PRIDE; Q9UUG2; -.
DR   EnsemblFungi; SPAC926.06c.1; SPAC926.06c.1:pep; SPAC926.06c.
DR   GeneID; 2543531; -.
DR   KEGG; spo:SPAC926.06c; -.
DR   PomBase; SPAC926.06c; -.
DR   VEuPathDB; FungiDB:SPAC926.06c; -.
DR   eggNOG; ENOG502QTY2; Eukaryota.
DR   HOGENOM; CLU_009538_0_0_1; -.
DR   InParanoid; Q9UUG2; -.
DR   OMA; GMSALWS; -.
DR   PhylomeDB; Q9UUG2; -.
DR   PRO; PR:Q9UUG2; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0000329; C:fungal-type vacuole membrane; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0019901; F:protein kinase binding; IBA:GO_Central.
DR   Gene3D; 3.80.10.10; -; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR025875; Leu-rich_rpt_4.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF12799; LRR_4; 1.
DR   Pfam; PF13855; LRR_8; 1.
DR   SMART; SM00369; LRR_TYP; 2.
DR   PROSITE; PS51450; LRR; 7.
PE   1: Evidence at protein level;
KW   Cytoplasm; Leucine-rich repeat; Membrane; Nucleus; Phosphoprotein;
KW   Reference proteome; Repeat; Vacuole.
FT   CHAIN           1..621
FT                   /note="Uncharacterized leucine-rich repeat-containing
FT                   protein C926.06c"
FT                   /id="PRO_0000312229"
FT   REPEAT          333..354
FT                   /note="LRR 1"
FT   REPEAT          357..379
FT                   /note="LRR 2"
FT   REPEAT          380..401
FT                   /note="LRR 3"
FT   REPEAT          404..425
FT                   /note="LRR 4"
FT   REPEAT          426..447
FT                   /note="LRR 5"
FT   REPEAT          451..472
FT                   /note="LRR 6"
FT   REGION          552..581
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         269
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   MOD_RES         271
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   MOD_RES         274
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   MOD_RES         290
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   MOD_RES         292
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
SQ   SEQUENCE   621 AA;  69485 MW;  0881543734AA5F8E CRC64;
     MGSTVDGEKY IRNLASYIRS HEKRFARAPY RAPNHSIFSD RPVQLQLTVH HLYYLLTKFE
     ELGVNTGPLN IRIENLHSET FPSDYTSFLN QSPKKNDFDD NMSLNSIVTM GSILSNVSSV
     WSIFSTAPSE ASETRNKQRI LAILRYIYSC FTKLPAISLV YNPKTPLISQ YEEFPLDTAV
     PITVFKNLSS LEIRGYDIRS IFGWDFLSTT LKSLILHHCD LADLSEVLIK LVLDDAELYR
     FRSSRQTYPQ QPNSQPCEQH PAHANLRRSV SLGSKDYLKS SHPPVHKTLS QSVLVLSKDG
     NASSSGGTEN QSANSSSSLM EKDAILSSSS WSQLLYLRCS SCKLKSIPKN VFLSLQSLVS
     LDLSGNELTE IPYALGELPQ LCSLNLASNK ITGCRTFYHI SLSHLQILVL SRNHLTSLSG
     LENVPSLEKL DIRDNSITDV VEFRRLVGNT NFEEAYLSLN PFTKTYSSYR ITIFNYFREY
     PGSKDIMLDG RGPGMLEKMY LSEKASAPER VISLNPVNQK SHSPAIKSSS TLRKASKTRI
     VDLSAPNSAV FSKNASGGDT SSNVSLLNGS ASEEIPQNTE SGQVFRKKIE MLRQEAGPEW
     VDALMKESVV KHKFRNKDES V