YG1A_SCHPO
ID YG1A_SCHPO Reviewed; 189 AA.
AC O94694;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=UPF0620 protein C83.10;
DE Flags: Precursor;
GN ORFNames=SPBC83.10;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC Single-pass type I membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the UPF0620 family. {ECO:0000305}.
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DR EMBL; CU329671; CAB36872.1; -; Genomic_DNA.
DR PIR; T40699; T40699.
DR RefSeq; NP_595642.1; NM_001021536.2.
DR AlphaFoldDB; O94694; -.
DR BioGRID; 277275; 1.
DR STRING; 4896.SPBC83.10.1; -.
DR MaxQB; O94694; -.
DR PaxDb; O94694; -.
DR EnsemblFungi; SPBC83.10.1; SPBC83.10.1:pep; SPBC83.10.
DR GeneID; 2540754; -.
DR KEGG; spo:SPBC83.10; -.
DR PomBase; SPBC83.10; -.
DR VEuPathDB; FungiDB:SPBC83.10; -.
DR HOGENOM; CLU_1462148_0_0_1; -.
DR InParanoid; O94694; -.
DR OMA; NNETAHV; -.
DR PhylomeDB; O94694; -.
DR PRO; PR:O94694; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0072546; C:EMC complex; ISO:PomBase.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0045048; P:protein insertion into ER membrane; IC:PomBase.
DR InterPro; IPR039163; EMC7.
DR InterPro; IPR019008; EMC7_beta_sandwich.
DR PANTHER; PTHR13605; PTHR13605; 1.
DR Pfam; PF09430; DUF2012; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..189
FT /note="UPF0620 protein C83.10"
FT /id="PRO_0000343218"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 189 AA; 21528 MW; 9A1A1D0D426AE97C CRC64;
MKLHTFLLLS VLCFAGCIQQ SLQAEVYGKV LTNTILPKIN LLSYDTRARL ISSNKTFETV
VERDGSFTFP NVPDEIYFLR LESIDYEFSE FHIIINESIV YPYYTSPAEK RPASSTAKNT
SYPIKVRAVL KRDYLKEPRK FSLIRLLKSP MMLLSLASVV LVFILPKLNI EAKALEQARL
AEAAEKKTA