YG23_SCHPO
ID YG23_SCHPO Reviewed; 598 AA.
AC O60162;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Uncharacterized protein C19F5.03;
DE EC=3.1.3.-;
GN ORFNames=SPBC19F5.03;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-46, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:16823372}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329671; CAA18651.1; -; Genomic_DNA.
DR PIR; T39821; T39821.
DR RefSeq; NP_596541.1; NM_001022462.2.
DR AlphaFoldDB; O60162; -.
DR SMR; O60162; -.
DR BioGRID; 276921; 5.
DR STRING; 4896.SPBC19F5.03.1; -.
DR iPTMnet; O60162; -.
DR MaxQB; O60162; -.
DR PaxDb; O60162; -.
DR PRIDE; O60162; -.
DR EnsemblFungi; SPBC19F5.03.1; SPBC19F5.03.1:pep; SPBC19F5.03.
DR GeneID; 2540393; -.
DR KEGG; spo:SPBC19F5.03; -.
DR PomBase; SPBC19F5.03; -.
DR VEuPathDB; FungiDB:SPBC19F5.03; -.
DR eggNOG; KOG1889; Eukaryota.
DR HOGENOM; CLU_003016_7_4_1; -.
DR InParanoid; O60162; -.
DR OMA; FRDINVH; -.
DR PhylomeDB; O60162; -.
DR Reactome; R-SPO-1483248; Synthesis of PIPs at the ER membrane.
DR Reactome; R-SPO-1660514; Synthesis of PIPs at the Golgi membrane.
DR PRO; PR:O60162; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005938; C:cell cortex; IDA:PomBase.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:PomBase.
DR GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; ISO:PomBase.
DR GO; GO:0030173; C:integral component of Golgi membrane; ISO:PomBase.
DR GO; GO:0005741; C:mitochondrial outer membrane; ISO:PomBase.
DR GO; GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IBA:GO_Central.
DR GO; GO:0046856; P:phosphatidylinositol dephosphorylation; ISO:PomBase.
DR InterPro; IPR002013; SAC_dom.
DR Pfam; PF02383; Syja_N; 1.
DR PROSITE; PS50275; SAC; 1.
PE 1: Evidence at protein level;
KW Endoplasmic reticulum; Hydrolase; Membrane; Phosphoprotein;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..598
FT /note="Uncharacterized protein C19F5.03"
FT /id="PRO_0000317230"
FT TRANSMEM 508..528
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 535..555
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 106..441
FT /note="SAC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00183"
FT MOD_RES 46
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 598 AA; 68713 MW; F3B3618D4C7F08E6 CRC64;
MVQFEANEKQ FKLRREDCCL TIDRESGAVS FEPDELKPVA RSKENSVTLF GSIKLKKDKY
LILATEKSSA AQILGHKIYR VHKFEVIPYR NLLADDQDEL DLYNLLQNHL KTGPFYFSYT
WDLTNSLQRS CTDEGKASPI LRSDKRFFWN EFASKDFIDL IGAHSEVSLF ITPMIYGFIT
SASTIVKGRT ITLALISRRS KQRAGTRYFT RGLDENGNPA NFNETEQITI VSDEKSEVTY
SHVQTRGSVP AFWAEVNNLR YKPLMVANSA SMAAAAAKKH FDEQISIYGD QVVVNLVNCK
GHELPIKQLY ENVIRRLDNP HIHYHYFDFH KECSHMRWDR VSLLLNEIQP ELEEQGYTTL
DTQKYRVLSR QNGVVRSNCM DCLDRTNVVQ SCIGRWVLTN QLRKCGIIGA THPLRSVIPL
DNIFCNIWSD NADYISLSYS GTGALKTDFT RTGIRTRKGA FNDFVNSAKR YILNNFYDGA
RQDAYDLVLG QFRPDVNFRY RLDLRPLTIR CVPYILLACL ILFFMTLFSR SSSTILPPSI
LLILTFLGIV ASLYYCFAHG LQFINWPRLL LPSFLRSDMT PEGRVFVINR QLASKHKV
