YG2A_YEAST
ID YG2A_YEAST Reviewed; 804 AA.
AC P53243; D6VUK1;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 21-SEP-2011, sequence version 2.
DT 03-AUG-2022, entry version 156.
DE RecName: Full=Zinc finger protein YGR067C;
GN OrderedLocusNames=YGR067C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169869;
RA Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J.,
RA Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M.,
RA Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L.,
RA Coblenz A., Coglievina M., Coissac E., Defoor E., Del Bino S., Delius H.,
RA Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P.,
RA Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M.,
RA Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A.,
RA Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K.,
RA Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P.,
RA Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E.,
RA Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K.,
RA Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A.,
RA Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S.,
RA Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M.,
RA Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C.,
RA Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M.,
RA Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M.,
RA Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y.,
RA Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L.,
RA Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D.,
RA Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F.,
RA Zaccaria P., Zimmermann M., Zollner A., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.";
RL Nature 387:81-84(1997).
RN [2]
RP GENOME REANNOTATION, AND SEQUENCE REVISION TO 795.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR EMBL; Z72852; CAA97069.1; -; Genomic_DNA.
DR EMBL; BK006941; DAA08162.2; -; Genomic_DNA.
DR PIR; S64362; S64362.
DR RefSeq; NP_011581.4; NM_001181196.4.
DR AlphaFoldDB; P53243; -.
DR SMR; P53243; -.
DR BioGRID; 33311; 46.
DR DIP; DIP-2819N; -.
DR IntAct; P53243; 12.
DR MINT; P53243; -.
DR STRING; 4932.YGR067C; -.
DR iPTMnet; P53243; -.
DR PaxDb; P53243; -.
DR PRIDE; P53243; -.
DR EnsemblFungi; YGR067C_mRNA; YGR067C; YGR067C.
DR GeneID; 852958; -.
DR KEGG; sce:YGR067C; -.
DR SGD; S000003299; YGR067C.
DR VEuPathDB; FungiDB:YGR067C; -.
DR eggNOG; KOG1721; Eukaryota.
DR HOGENOM; CLU_350296_0_0_1; -.
DR InParanoid; P53243; -.
DR OMA; LLWETIW; -.
DR BioCyc; YEAST:G3O-30781-MON; -.
DR PRO; PR:P53243; -.
DR Proteomes; UP000002311; Chromosome VII.
DR RNAct; P53243; protein.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0043565; F:sequence-specific DNA binding; HDA:SGD.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF00096; zf-C2H2; 1.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF57667; SSF57667; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 4: Predicted;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Zinc;
KW Zinc-finger.
FT CHAIN 1..804
FT /note="Zinc finger protein YGR067C"
FT /id="PRO_0000046863"
FT ZN_FING 8..30
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 36..59
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT REGION 782..804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 804 AA; 92250 MW; BB936C265B7B263F CRC64;
MAAGQKKYIC SFCLKPFSRS EHKIRHERSH AGVKPFQCQV CKHSFVRRDL LQRHIRTVHR
TFLLSSYASM TGDKADIPVS LGVGDVDSTS PRDIKMETLV NSMIKVNSGL INIHYHSSNV
EKMDKQQRCV IGKESSSLKK GKSRFKQVKS RLESSISVKI LQEYSLDFIS SRDILTFFRM
GVSHLVENKI FQNFFPDLFS SLQNDELVES FWINKPFGLI IACLGMSISL NQDSQKLWFI
CCTNLYASSS KHDNDFDTED ILSQTEQHDV FALILFYSLL VMLENNIPVS NSIKKFDVFS
MLQDILKPFT VASSSYHYLN SKENAWFIFD LWVNILRDSN NFNNDSLLIF GWFVNQEFIS
SNPLKDFIYK GPSMSTTDLT LKHINILADS AYVYFIIKKT YPQELPSDFR VHDLLVYLNE
CFVMQQPIKP ETSANPSLFA NVMNARITDC KSKSNWLLWE TIWFEFINNL TLRNGTTRNI
WFIDNFPQVS TSCLLHHSSS FVDETLITTN LSIISMLLNL KSFTLASLNP RNIQLITDIV
SFQLKLFSSE LIASSDVSPS QVSQLLVNPN VHLMLYFWFD TIYVQRQSYL SSTEKEEFEK
VEVFVNDYII THQKNLVTDL HSILFDFWSD SFIAYHILLH AIVSSLRDNI LYPYLIYSPH
LNDQTKALLT DISNWSCFAL QQPFRKTSRG SLSGASDMKS FSVASCLPLS PNFLKRDSNC
NKILLPPLDI KAIEPISTSN YTYVNSAPKQ QEKEQPLLRA TGNNINLVQT IVVPPQVNME
SQEFSASSTD NKQSKNIEIF SQIK
