YG51_YEAST
ID YG51_YEAST Reviewed; 785 AA.
AC P50089; D6VV17;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Uncharacterized protein YGR237C;
GN OrderedLocusNames=YGR237C; ORFNames=G8581;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8701610;
RX DOI=10.1002/(sici)1097-0061(19960330)12:4<385::aid-yea910>3.0.co;2-g;
RA van der Aart Q.J.M., Kleine K., Steensma H.Y.;
RT "Sequence analysis of the 43 kb CRM1-YLM9-PET54-DIE2-SMI1-PHO81-YHB4-PFK1
RT region from the right arm of Saccharomyces cerevisiae chromosome VII.";
RL Yeast 12:385-390(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169869;
RA Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J.,
RA Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M.,
RA Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L.,
RA Coblenz A., Coglievina M., Coissac E., Defoor E., Del Bino S., Delius H.,
RA Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P.,
RA Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M.,
RA Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A.,
RA Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K.,
RA Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P.,
RA Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E.,
RA Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K.,
RA Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A.,
RA Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S.,
RA Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M.,
RA Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C.,
RA Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M.,
RA Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M.,
RA Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y.,
RA Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L.,
RA Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D.,
RA Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F.,
RA Zaccaria P., Zimmermann M., Zollner A., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.";
RL Nature 387:81-84(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-667, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ADR376;
RX PubMed=17330950; DOI=10.1021/pr060559j;
RA Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,
RA Elias J.E., Gygi S.P.;
RT "Large-scale phosphorylation analysis of alpha-factor-arrested
RT Saccharomyces cerevisiae.";
RL J. Proteome Res. 6:1190-1197(2007).
RN [6]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-215 AND SER-667, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19779198; DOI=10.1126/science.1172867;
RA Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT into evolution.";
RL Science 325:1682-1686(2009).
CC -!- MISCELLANEOUS: Present with 1050 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; X87941; CAA61187.1; -; Genomic_DNA.
DR EMBL; Z73022; CAA97265.1; -; Genomic_DNA.
DR EMBL; BK006941; DAA08328.1; -; Genomic_DNA.
DR PIR; S57702; S57702.
DR RefSeq; NP_011753.1; NM_001181366.1.
DR AlphaFoldDB; P50089; -.
DR BioGRID; 33489; 152.
DR DIP; DIP-3933N; -.
DR IntAct; P50089; 4.
DR MINT; P50089; -.
DR STRING; 4932.YGR237C; -.
DR iPTMnet; P50089; -.
DR MaxQB; P50089; -.
DR PaxDb; P50089; -.
DR PRIDE; P50089; -.
DR EnsemblFungi; YGR237C_mRNA; YGR237C; YGR237C.
DR GeneID; 853152; -.
DR KEGG; sce:YGR237C; -.
DR SGD; S000003469; YGR237C.
DR VEuPathDB; FungiDB:YGR237C; -.
DR eggNOG; ENOG502QSA6; Eukaryota.
DR HOGENOM; CLU_014122_0_0_1; -.
DR InParanoid; P50089; -.
DR OMA; WSSVDWY; -.
DR BioCyc; YEAST:G3O-30915-MON; -.
DR PRO; PR:P50089; -.
DR Proteomes; UP000002311; Chromosome VII.
DR RNAct; P50089; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..785
FT /note="Uncharacterized protein YGR237C"
FT /id="PRO_0000202854"
FT REGION 53..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 571..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 631..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 705..723
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 724..738
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 742..758
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 215
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19779198"
FT MOD_RES 667
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:17330950,
FT ECO:0007744|PubMed:19779198"
SQ SEQUENCE 785 AA; 89241 MW; E619637EAE223BF5 CRC64;
MSSAKTFTKH ISFDDLAPSL IDDQATIIKN DSHHVGLNNH FLHIPPQFNP VYKNTLTGSH
GSNDLATDES LDSPEDEEAS SPLQLGTPTS TTSGVPHFYT QVFSPAAHDP SKSYLRSPSV
ERSRSESPMF RSRRRTSVRL PPPPKVSVLK KSRKAADEQG PIDDIDIGDL DFELERKMTK
MTERNTQKNS GSRKGYTQAA FANLNEVEDR IETKSMVDLS ESENMESSKK RSKSFAGMTD
EELAKLEEFY ISKGRSNKTK IDQFDFGEQV PVYLNTTESK TDSSNVTDPL AAIYPSRPTI
VHNAISMTID HPDYENYISN TKEKLNCKDK DDDVDLRVVS CYISGRRYTW SSVDWYVENL
TRNGDHLVII TTIPEFEAKI DTLAYKEKRR HRLERMTSNT SESMTTASHS LIGPDLSSPL
STGIRIEAIH NEAKQTCSDI LNYYARRLAT KIVRISIEMV KENSTRSAII SATSLYRPSL
QVISTVSANI QIKFRNGKVK LPFFLMKHFA MPAFVVPFEF IKPELLIKPR VDKDEQDNSD
DLKTEVRKKE RLQWLSALIR RTLENPFTKH KVVDSDDEES DSDESVTSVN EYFPISPEKK
EEMEFFDKMG YVRPKPSRQV LLDDNTLMKY DSSGRKLTPI ESRNSRRSSK RSSRIQFNNN
GIYKVKSMVD DIYNHETAST PHIKTALKWD NEDPKMKFTS HPMRKTKSAG LSPRTSSTSS
SSGQRKAHHH HHHHNHVSRT KTTESTKSGN SKKDSSSSST NDHQFKRSEK KKKSKFGSIF
KKVFG
