YG5X_YEAST
ID YG5X_YEAST Reviewed; 341 AA.
AC P53336; D6VV60;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Putative methyltransferase YGR283C {ECO:0000305};
DE EC=2.1.1.- {ECO:0000305};
GN OrderedLocusNames=YGR283C {ECO:0000312|SGD:S000003515};
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 96604 / S288c / FY1679;
RX PubMed=9090054;
RX DOI=10.1002/(sici)1097-0061(19970315)13:3<251::aid-yea63>3.0.co;2-r;
RA Volckaert G., Voet M., Robben J.;
RT "Sequence analysis of a near-subtelomeric 35.4 kb DNA segment on the right
RT arm of chromosome VII from Saccharomyces cerevisiae carrying the MAL1 locus
RT reveals 15 complete open reading frames, including ZUO1, BGL2 and BIO2
RT genes and an ABC transporter gene.";
RL Yeast 13:251-259(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169869;
RA Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J.,
RA Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M.,
RA Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L.,
RA Coblenz A., Coglievina M., Coissac E., Defoor E., Del Bino S., Delius H.,
RA Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P.,
RA Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M.,
RA Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A.,
RA Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K.,
RA Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P.,
RA Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E.,
RA Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K.,
RA Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A.,
RA Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S.,
RA Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M.,
RA Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C.,
RA Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M.,
RA Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M.,
RA Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y.,
RA Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L.,
RA Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D.,
RA Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F.,
RA Zaccaria P., Zimmermann M., Zollner A., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.";
RL Nature 387:81-84(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 2820 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC superfamily. {ECO:0000305}.
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DR EMBL; Z73068; CAA97314.1; -; Genomic_DNA.
DR EMBL; BK006941; DAA08371.1; -; Genomic_DNA.
DR PIR; S64618; S64618.
DR RefSeq; NP_011799.3; NM_001181412.3.
DR AlphaFoldDB; P53336; -.
DR SMR; P53336; -.
DR BioGRID; 33533; 88.
DR DIP; DIP-5565N; -.
DR MINT; P53336; -.
DR STRING; 4932.YGR283C; -.
DR MaxQB; P53336; -.
DR PaxDb; P53336; -.
DR PRIDE; P53336; -.
DR EnsemblFungi; YGR283C_mRNA; YGR283C; YGR283C.
DR GeneID; 853200; -.
DR KEGG; sce:YGR283C; -.
DR SGD; S000003515; YGR283C.
DR VEuPathDB; FungiDB:YGR283C; -.
DR eggNOG; KOG3925; Eukaryota.
DR GeneTree; ENSGT00390000016537; -.
DR HOGENOM; CLU_061859_0_0_1; -.
DR InParanoid; P53336; -.
DR OMA; YLKCAST; -.
DR BioCyc; YEAST:G3O-30945-MON; -.
DR PRO; PR:P53336; -.
DR Proteomes; UP000002311; Chromosome VII.
DR RNAct; P53336; protein.
DR GO; GO:0005730; C:nucleolus; HDA:SGD.
DR GO; GO:0008168; F:methyltransferase activity; ISS:SGD.
DR GO; GO:0032259; P:methylation; IC:SGD.
DR CDD; cd18086; HsC9orf114-like; 1.
DR Gene3D; 3.40.1280.10; -; 2.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR003750; Put_MeTrfase.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR PANTHER; PTHR12150; PTHR12150; 1.
DR Pfam; PF02598; Methyltrn_RNA_3; 1.
DR SUPFAM; SSF75217; SSF75217; 1.
PE 1: Evidence at protein level;
KW Methyltransferase; Nucleus; Reference proteome; Transferase.
FT CHAIN 1..341
FT /note="Putative methyltransferase YGR283C"
FT /id="PRO_0000202872"
SQ SEQUENCE 341 AA; 38546 MW; 3C91F8EF9C24EFC9 CRC64;
MAVKHKSESL KHEEGAAKKA KTGLLKLKKI MDIESNVVKY SICIPTTVID NCNNLEQVTF
TAYQIARTAV LFNVQEIIVL DQSKDKKHEK KSRSKETISD CLLLATLLQY FVTPPNLLDT
TFKKKNKLYL KCASTFPPLN QLPFMNASAE QHYKEGLSIA RDSSKGKSDD ALTNLVYIGK
NQIITLSNQN IPNTARVTVD TERKEVVSPI DAYKGKPLGY HVRMASTLNE VSEGYTKIVW
VNSGDFHYDE ELSKYHKVET KLPYIAKLKK SSTSEKPCNI LLIFGKWGHL KRCFRRSDLE
SSSLHHYFSG QLQFPASVPQ GNIPIQDSLP IALTMFQRWA S
