ID   YG66_SCHPO              Reviewed;         556 AA.
AC   Q1MTR5;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Uncharacterized RING finger membrane protein C15C4.06c;
GN   ORFNames=SPBC15C4.06c, SPBC21H7.01c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000305}; Single-pass
CC       membrane protein {ECO:0000305}. Cell membrane {ECO:0000305}; Single-
CC       pass type I membrane protein {ECO:0000305}.
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DR   EMBL; CU329671; CAA18897.1; -; Genomic_DNA.
DR   RefSeq; NP_595926.1; NM_001021834.2.
DR   AlphaFoldDB; Q1MTR5; -.
DR   BioGRID; 276337; 55.
DR   STRING; 4896.SPBC15C4.06c.1; -.
DR   iPTMnet; Q1MTR5; -.
DR   MaxQB; Q1MTR5; -.
DR   PaxDb; Q1MTR5; -.
DR   PRIDE; Q1MTR5; -.
DR   EnsemblFungi; SPBC15C4.06c.1; SPBC15C4.06c.1:pep; SPBC15C4.06c.
DR   GeneID; 2539787; -.
DR   KEGG; spo:SPBC15C4.06c; -.
DR   PomBase; SPBC15C4.06c; -.
DR   VEuPathDB; FungiDB:SPBC15C4.06c; -.
DR   eggNOG; KOG0800; Eukaryota.
DR   HOGENOM; CLU_490160_0_0_1; -.
DR   InParanoid; Q1MTR5; -.
DR   OMA; LYRELPC; -.
DR   PRO; PR:Q1MTR5; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0032153; C:cell division site; HDA:PomBase.
DR   GO; GO:0051286; C:cell tip; HDA:PomBase.
DR   GO; GO:0000324; C:fungal-type vacuole; HDA:PomBase.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; ISM:PomBase.
DR   GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR   GO; GO:0070647; P:protein modification by small protein conjugation or removal; IC:PomBase.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   Pfam; PF13639; zf-RING_2; 1.
DR   SMART; SM00184; RING; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Cell membrane; Ligase; Membrane; Metal-binding; Reference proteome;
KW   Transmembrane; Transmembrane helix; Vacuole; Zinc; Zinc-finger.
FT   CHAIN           1..556
FT                   /note="Uncharacterized RING finger membrane protein
FT                   C15C4.06c"
FT                   /id="PRO_0000352823"
FT   TRANSMEM        379..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   ZN_FING         498..541
FT                   /note="RING-type; atypical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   REGION          69..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        72..95
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        96..129
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   556 AA;  62311 MW;  7CA076062F02B067 CRC64;
     MHLCNNQLLD HLDCNAVYRG YVSQENKVKR RKRLFNAIRK LWNERRRYRM PKDESISPTP
     ISYSFRSLRR GHTSGHASEH TSSSRSSHDE SDSMSSSSES DSDSVSSESN PKSYSDSSTS
     SARSSSTSGS ISLYDDYYPA YSSNAPNTAI SNYVSSGLSY YGNSSIIMNA VEYNQFFPLT
     ITTLIVKNNK NVVSNLPKNV SFYFHSDNTV LLNEYYKSLS KLKNNFRGII YKTTPYGSCN
     DTESLQVDTK GSVWFRDVSN MGSSGLIAFA PFDYCAPMHV LQAVQDRAKA ILFYNASTAS
     NSLTNFDHFE DAVDMITFET LPMALISYEN GIAFEKILNE YSASSLNSVQ DGGALVEYFG
     NIDATARLGV IISKEPKLLG LYIFIGVLLG LIGVIGLFIC LHFSGAMNGF YRLLNRHGIP
     VQERIVNIGP NKPENRVTKE MLDTLPVRMF SGPHLANPND ELVYEKDWKL DKSESFDGQG
     NVVTTAERGS KYFDQRECTI CLCEYSEESP LYRELPCHHI FHPACIDPYL LKNSDLCPLC
     KQSVTNMLEN ASEDNV