ID   YGAY_ECO57              Reviewed;         394 AA.
AC   Q8X4V6;
DT   10-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Uncharacterized transporter YgaY;
GN   Name=ygaY; OrderedLocusNames=Z3982, ECs3543;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE005174; AAG57790.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB36966.1; -; Genomic_DNA.
DR   PIR; B85916; B85916.
DR   PIR; G91071; G91071.
DR   RefSeq; NP_311570.1; NC_002695.1.
DR   RefSeq; WP_000165714.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; Q8X4V6; -.
DR   SMR; Q8X4V6; -.
DR   STRING; 155864.EDL933_3847; -.
DR   EnsemblBacteria; AAG57790; AAG57790; Z3982.
DR   EnsemblBacteria; BAB36966; BAB36966; ECs_3543.
DR   GeneID; 914741; -.
DR   KEGG; ece:Z3982; -.
DR   KEGG; ecs:ECs_3543; -.
DR   PATRIC; fig|386585.9.peg.3698; -.
DR   eggNOG; COG2814; Bacteria.
DR   HOGENOM; CLU_001265_23_0_6; -.
DR   OMA; VQTTVAY; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 2.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..394
FT                   /note="Uncharacterized transporter YgaY"
FT                   /id="PRO_0000173408"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        243..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        337..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        364..384
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   394 AA;  41654 MW;  2707B7321E93BE7C CRC64;
     MTKPNHELSP ALIVLMSIAT GLAVASNYYA QPLLDTIARN FSLSASSAGF IVTAAQLGYA
     AGLLFLVPLG DMFERRRLIV SMTLLAAGGM LITASSQSLA MMILGTALTG LFSVVAQILV
     PLAATLASPD KRGKVVGTIM SGLLLGILLA RTVAGLLANL GGWRTVFWVA SVLMALMALA
     LWRGLPQMKS ETHLNYPQLL GSVFSMFISN KILRTRALLG CLTFANFSIL WTSMAFLLAA
     PPFNYSDGVI GLFGLAGAAG ALGARPAGGF ADKGKSHHTT TFGLLLLLLS WLAIWFGHTS
     VLALIIGILV LDLTVQGVHI TNQTVIYRIH PDARNRLTAG YMTSYFIGGA AGSLISASAW
     QHGGWAGVCL AGATIALVNL LVWWRGFHRQ EAAN