YGBE_ECOLI
ID YGBE_ECOLI Reviewed; 107 AA.
AC P46141; Q2MA80; Q46895;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Inner membrane protein YgbE;
GN Name=ygbE; OrderedLocusNames=b2749, JW2719;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-81.
RC STRAIN=K12;
RX PubMed=1316900; DOI=10.1016/s0021-9258(19)50034-5;
RA Leyh T.S., Vogt T.F., Suo Y.;
RT "The DNA sequence of the sulfate activation locus from Escherichia coli K-
RT 12.";
RL J. Biol. Chem. 267:10405-10410(1992).
RN [4]
RP IDENTIFICATION.
RX PubMed=7567469; DOI=10.1093/nar/23.17.3554;
RA Borodovsky M., McIninch J., Koonin E.V., Rudd K.E., Medigue C., Danchin A.;
RT "Detection of new genes in a bacterial genome using Markov models for three
RT gene classes.";
RL Nucleic Acids Res. 23:3554-3562(1995).
RN [5]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U29579; AAA69259.1; -; Genomic_DNA.
DR EMBL; U00096; AAC75791.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76826.1; -; Genomic_DNA.
DR EMBL; M74586; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; A65056; A65056.
DR RefSeq; NP_417229.1; NC_000913.3.
DR RefSeq; WP_001246104.1; NZ_STEB01000027.1.
DR AlphaFoldDB; P46141; -.
DR BioGRID; 4262282; 13.
DR STRING; 511145.b2749; -.
DR PaxDb; P46141; -.
DR EnsemblBacteria; AAC75791; AAC75791; b2749.
DR EnsemblBacteria; BAE76826; BAE76826; BAE76826.
DR GeneID; 66673377; -.
DR GeneID; 947268; -.
DR KEGG; ecj:JW2719; -.
DR KEGG; eco:b2749; -.
DR PATRIC; fig|1411691.4.peg.3991; -.
DR EchoBASE; EB2569; -.
DR eggNOG; ENOG5032TB7; Bacteria.
DR HOGENOM; CLU_172652_0_0_6; -.
DR OMA; LMLYTWP; -.
DR PhylomeDB; P46141; -.
DR BioCyc; EcoCyc:EG12707-MON; -.
DR PRO; PR:P46141; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR InterPro; IPR022721; DUF3561.
DR Pfam; PF12084; DUF3561; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..107
FT /note="Inner membrane protein YgbE"
FT /id="PRO_0000169311"
FT TOPO_DOM 1..20
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 44..52
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 53..75
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 76..86
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..106
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 107
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT CONFLICT 67..81
FT /note="VAVVVGIALHSLMDG -> SRSGGDCAAFIDGRK (in Ref. 1)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 107 AA; 12017 MW; E3ED0F889EA9C21F CRC64;
MRNSHNITLT NNDSLTEDEE TTWSLPGAVV GFISWLFALA MPMLIYGSNT LFFFIYTWPF
FLALMPVAVV VGIALHSLMD GKLRYSIVFT LVTVGIMFGA LFMWLLG
