YGBN_ECOLI
ID YGBN_ECOLI Reviewed; 454 AA.
AC Q46892; Q2MA89;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Inner membrane permease YgbN;
GN Name=ygbN; OrderedLocusNames=b2740, JW2710;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [3]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the GntP permease family. {ECO:0000305}.
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DR EMBL; U29579; AAA69250.1; -; Genomic_DNA.
DR EMBL; U00096; AAC75782.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76817.1; -; Genomic_DNA.
DR PIR; H65054; H65054.
DR RefSeq; NP_417220.1; NC_000913.3.
DR RefSeq; WP_000104441.1; NZ_LN832404.1.
DR AlphaFoldDB; Q46892; -.
DR BioGRID; 4260990; 160.
DR STRING; 511145.b2740; -.
DR TCDB; 2.A.8.1.7; the gluconate:h(+) symporter (gntp) family.
DR PaxDb; Q46892; -.
DR PRIDE; Q46892; -.
DR DNASU; 947208; -.
DR EnsemblBacteria; AAC75782; AAC75782; b2740.
DR EnsemblBacteria; BAE76817; BAE76817; BAE76817.
DR GeneID; 947208; -.
DR KEGG; ecj:JW2710; -.
DR KEGG; eco:b2740; -.
DR PATRIC; fig|1411691.4.peg.4000; -.
DR EchoBASE; EB2911; -.
DR eggNOG; COG2610; Bacteria.
DR HOGENOM; CLU_027949_0_2_6; -.
DR InParanoid; Q46892; -.
DR OMA; DIRAEVY; -.
DR PhylomeDB; Q46892; -.
DR BioCyc; EcoCyc:B2740-MON; -.
DR PRO; PR:Q46892; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0015128; F:gluconate transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR003474; Glcn_transporter.
DR PANTHER; PTHR30354; PTHR30354; 1.
DR Pfam; PF02447; GntP_permease; 1.
DR PIRSF; PIRSF002746; Gluconate_transporter; 1.
DR TIGRFAMs; TIGR00791; gntP; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..454
FT /note="Inner membrane permease YgbN"
FT /id="PRO_0000061943"
FT TOPO_DOM 1
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 2..22
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 23..27
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 49..52
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 74..108
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 130..137
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 159..174
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 196..235
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 236..256
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 257..273
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 295..305
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 327..341
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 342..362
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 363..383
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 384..404
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 405..433
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 434..454
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 454 AA; 46770 MW; 567B17E06586C2B9 CRC64;
MSTITLLCIA LAGVIMLLLL VIKAKVQPFV ALLLVSLLVA LAAGIPAGEV GKVMIAGMGG
VLGSVTIIIG LGAMLGRMIE HSGGAESLAN YFSRKLGDKR TIAALTLAAF FLGIPVFFDV
GFIILAPIIY GFAKVAKISP LKFGLPVAGI MLTVHVAVPP HPGPVAAAGL LHADIGWLTI
IGIAISIPVG VVGYFAAKII NKRQYAMSVE VLEQMQLAPA SEEGATKLSD KINPPGVALV
TSLIVIPIAI IMAGTVSATL MPPSHPLLGT LQLIGSPMVA LMIALVLAFW LLALRRGWSL
QHTSDIMGSA LPTAAVVILV TGAGGVFGKV LVESGVGKAL ANMLQMIDLP LLPAAFIISL
ALRASQGSAT VAILTTGGLL SEAVMGLNPI QCVLVTLAAC FGGLGASHIN DSGFWIVTKY
LGLSVADGLK TWTVLTTILG FTGFLITWCV WAVI
